Detalhe da pesquisa
1.
UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors.
Cell
; 176(3): 505-519.e22, 2019 01 24.
Artigo
Inglês
| MEDLINE | ID: mdl-30612738
2.
The serendipitous dawn of DNA repair.
Nat Rev Mol Cell Biol
; 21(10): 569, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32807976
3.
The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.
Mol Cell
; 69(5): 866-878.e7, 2018 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29499138
4.
Phosphoproteomics reveals novel modes of function and inter-relationships among PIKKs in response to genotoxic stress.
EMBO J
; 40(2): e104400, 2021 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33215756
5.
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.
Nat Rev Mol Cell Biol
; 14(4): 197-210, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23486281
6.
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.
Nat Rev Mol Cell Biol
; 14(4): 197-210, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23847781
7.
USP10: friend and foe.
Cell
; 140(3): 308-10, 2010 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-20144755
8.
Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.
Nucleic Acids Res
; 46(2): 730-747, 2018 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-29253183
9.
Corrigendum: The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.
Genes Dev
; 31(18): 1926, 2017 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29051390
10.
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.
Mol Cell
; 41(5): 529-42, 2011 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-21362549
11.
Systemic DNA damage responses in aging and diseases.
Semin Cancer Biol
; 37-38: 26-35, 2016 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26773346
12.
The COP9 signalosome is vital for timely repair of DNA double-strand breaks.
Nucleic Acids Res
; 43(9): 4517-30, 2015 May 19.
Artigo
Inglês
| MEDLINE | ID: mdl-25855810
13.
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.
Mol Cell
; 31(2): 167-77, 2008 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-18657500
14.
Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK.
EMBO J
; 28(23): 3667-80, 2009 Dec 02.
Artigo
Inglês
| MEDLINE | ID: mdl-19851285
15.
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway.
Nat Cell Biol
; 8(8): 870-6, 2006 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-16862143
16.
ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair.
EMBO Rep
; 12(7): 713-9, 2011 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21637298
17.
ATM and related protein kinases: safeguarding genome integrity.
Nat Rev Cancer
; 3(3): 155-68, 2003 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-12612651
18.
SPIKE: a database of highly curated human signaling pathways.
Nucleic Acids Res
; 39(Database issue): D793-9, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-21097778
19.
Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks.
Proc Natl Acad Sci U S A
; 107(5): 2207-12, 2010 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-20133864
20.
Accelerated replicative senescence of ataxia-telangiectasia skin fibroblasts is retained at physiologic oxygen levels, with unique and common transcriptional patterns.
Aging Cell
; 22(8): e13869, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37254625