Detalhe da pesquisa
1.
APOE genotypes modify the obesity paradox in dementia.
J Neurol Neurosurg Psychiatry
; 94(9): 670-680, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37414536
2.
Deletion of B-cell translocation gene 2 (BTG2) alters the responses of glial cells in white matter to chronic cerebral hypoperfusion.
J Neuroinflammation
; 18(1): 86, 2021 Apr 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33812385
3.
Increased levels of Aß42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes.
FASEB J
; 34(2): 2425-2435, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31907998
4.
ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components.
Arterioscler Thromb Vasc Biol
; 40(1): 128-144, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31665905
5.
Oncological outcomes for patients with locally advanced prostate cancer treated with neoadjuvant endocrine and external-beam radiation therapy followed by adjuvant continuous/intermittent endocrine therapy in an open-label, randomized, phase 3 trial.
Cancer
; 126(17): 3961-3971, 2020 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32573779
6.
Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression.
Brain
; 142(4): 1077-1092, 2019 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30770921
7.
Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways.
Proc Natl Acad Sci U S A
; 114(33): E6962-E6971, 2017 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28701379
8.
APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes.
Hum Mol Genet
; 26(14): 2690-2700, 2017 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28444230
9.
The Roles of Apolipoprotein E, Lipids, and Glucose in the Pathogenesis of Alzheimer's Disease.
Adv Exp Med Biol
; 1128: 85-101, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31062326
10.
5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway.
Int J Mol Sci
; 20(6)2019 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-30934555
11.
Distinct spatiotemporal accumulation of N-truncated and full-length amyloid-ß42 in Alzheimer's disease.
Brain
; 140(12): 3301-3316, 2017 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29161341
12.
ABCA7 Deficiency Accelerates Amyloid-ß Generation and Alzheimer's Neuronal Pathology.
J Neurosci
; 36(13): 3848-59, 2016 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-27030769
13.
Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies.
J Lipid Res
; 58(7): 1267-1281, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28381441
14.
Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model.
Hum Mol Genet
; 24(21): 6198-212, 2015 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26276810
15.
APOE2 eases cognitive decline during Aging: Clinical and preclinical evaluations.
Ann Neurol
; 79(5): 758-774, 2016 May.
Artigo
Inglês
| MEDLINE | ID: mdl-26933942
16.
Apolipoprotein E Inhibits Cerebrovascular Pericyte Mobility through a RhoA Protein-mediated Pathway.
J Biol Chem
; 290(22): 14208-17, 2015 May 29.
Artigo
Inglês
| MEDLINE | ID: mdl-25903128
17.
Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.
Acta Neuropathol
; 132(2): 225-234, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27179972
18.
Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.
J Biol Chem
; 289(16): 11282-11292, 2014 Apr 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24599963
19.
Synthetic ceramide analogues increase amyloid-ß 42 production by modulating γ-secretase activity.
Biochem Biophys Res Commun
; 457(2): 194-9, 2015 Feb 06.
Artigo
Inglês
| MEDLINE | ID: mdl-25545059
20.
Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer's disease.
Brain
; 137(Pt 5): 1533-49, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24625695