Detalhe da pesquisa
1.
Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors.
Bioorg Med Chem Lett
; 26(19): 4606-4612, 2016 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27578246
2.
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor.
Proc Natl Acad Sci U S A
; 106(43): 18114-9, 2009 Oct 27.
Artigo
Inglês
| MEDLINE | ID: mdl-19822747
3.
Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor.
Bioorg Med Chem Lett
; 21(20): 6188-94, 2011 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21903390
4.
Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists.
Bioorg Med Chem Lett
; 19(1): 158-62, 2009 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19019676
5.
Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administration.
Bioorg Med Chem Lett
; 19(5): 1380-5, 2009 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19195882