Detalhe da pesquisa
1.
Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.
Cell
; 147(6): 1340-54, 2011 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-22153077
2.
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme.
Cell
; 145(7): 1075-87, 2011 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-21683433
3.
SCFFBXW7 regulates G2-M progression through control of CCNL1 ubiquitination.
EMBO Rep
; 23(12): e55044, 2022 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36278408
4.
MEK drives BRAF activation through allosteric control of KSR proteins.
Nature
; 554(7693): 549-553, 2018 02 22.
Artigo
Inglês
| MEDLINE | ID: mdl-29433126
5.
High Accuracy Prediction of PROTAC Complex Structures.
J Am Chem Soc
; 145(13): 7123-7135, 2023 04 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36961978
6.
Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function.
Mol Cell
; 59(6): 970-83, 2015 Sep 17.
Artigo
Inglês
| MEDLINE | ID: mdl-26344097
7.
The structural and functional workings of KEOPS.
Nucleic Acids Res
; 49(19): 10818-10834, 2021 11 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34614169
8.
A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
Proc Natl Acad Sci U S A
; 117(40): 24802-24812, 2020 10 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32958664
9.
Functional characterization of a PROTAC directed against BRAF mutant V600E.
Nat Chem Biol
; 16(11): 1170-1178, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32778845
10.
Remembering a pioneer in biotechnology.
Nature
; 600(7889): 386, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34907398
11.
The structural basis of modified nucleosome recognition by 53BP1.
Nature
; 536(7614): 100-3, 2016 08 04.
Artigo
Inglês
| MEDLINE | ID: mdl-27462807
12.
Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol Cell
; 53(2): 221-34, 2014 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-24462203
13.
OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug.
Proc Natl Acad Sci U S A
; 116(11): 5071-5076, 2019 03 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30814222
14.
Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids.
J Biol Chem
; 295(14): 4526-4540, 2020 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32086379
15.
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function.
Mol Cell
; 45(3): 384-97, 2012 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-22325355
16.
Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases.
Proc Natl Acad Sci U S A
; 114(6): 1311-1316, 2017 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28115697
17.
Inhibition of RAS function through targeting an allosteric regulatory site.
Nat Chem Biol
; 13(1): 62-68, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-27820802
18.
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.
Nature
; 499(7456): 50-4, 2013 Jul 04.
Artigo
Inglês
| MEDLINE | ID: mdl-23760478
19.
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature
; 498(7454): 318-24, 2013 Jun 20.
Artigo
Inglês
| MEDLINE | ID: mdl-23708998
20.
Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation.
Mol Cell Proteomics
; 16(6): 1111-1125, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28373297