Detalhe da pesquisa
1.
A phase I study of 17-allylamino-17-demethoxygeldanamycin combined with paclitaxel in patients with advanced solid malignancies.
Clin Cancer Res
; 14(11): 3456-61, 2008 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18519777
2.
A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells.
Mol Cancer Ther
; 7(2): 330-40, 2008 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-18245669
3.
Cell-based and biochemical structure-activity analyses of analogs of the microtubule stabilizer dictyostatin.
Mol Pharmacol
; 73(3): 718-26, 2008 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-18073274
4.
Total synthesis and biological evaluation of C16 analogs of (-)-dictyostatin.
J Med Chem
; 50(13): 2951-66, 2007 Jun 28.
Artigo
Inglês
| MEDLINE | ID: mdl-17542572
5.
Synthesis and biological evaluation of (-)-dictyostatin and stereoisomers.
Tetrahedron
; 63(35): 8537-8562, 2007 Aug 27.
Artigo
Inglês
| MEDLINE | ID: mdl-18728696
6.
Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product.
Chem Biol Drug Des
; 67(1): 66-73, 2006 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-16492150
7.
The benzo[c]phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1.
J Biol Chem
; 280(19): 19078-86, 2005 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-15753082