Detalhe da pesquisa
1.
Targeting the A3 adenosine receptor to treat hepatocellular carcinoma: anti-cancer and hepatoprotective effects.
Purinergic Signal
; 19(3): 513-522, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36781824
2.
Efficacy, Safety, Pharmacokinetics, and Microbiome Changes of Ibezapolstat in Adults with Clostridioides difficile Infection: A Phase 2a Multicenter Clinical Trial.
Clin Infect Dis
; 75(7): 1164-1170, 2022 09 30.
Artigo
Inglês
| MEDLINE | ID: mdl-35134880
3.
Functional and Metagenomic Evaluation of Ibezapolstat for Early Evaluation of Anti-Recurrence Effects in Clostridioides difficile Infection.
Antimicrob Agents Chemother
; 66(8): e0224421, 2022 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35862742
4.
A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects.
J Antimicrob Chemother
; 75(12): 3635-3643, 2020 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32892222
5.
Discovery and development of DNA polymerase IIIC inhibitors to treat Gram-positive infections.
Bioorg Med Chem
; 27(15): 3209-3217, 2019 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31221610
6.
Treatment of Plaque-Type Psoriasis With Oral CF101: Data from a Phase II/III Multicenter, Randomized, Controlled Trial.
J Drugs Dermatol
; 15(8): 931-8, 2016 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27537992
7.
A phase 1 open-label, sequential dose-escalation study investigating the safety, tolerability, and pharmacokinetics of intravenous TLC388 administered to patients with advanced solid tumors.
Invest New Drugs
; 32(3): 445-51, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24271274
8.
A longterm complete response to namodenoson in liver cancer with ChildPugh B cirrhosis: A case report.
Exp Ther Med
; 27(6): 263, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38756903
9.
CF102 for the treatment of hepatocellular carcinoma: a phase I/II, open-label, dose-escalation study.
Oncologist
; 18(1): 25-6, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23299770
10.
Randomised clinical trial: A phase 2 double-blind study of namodenoson in non-alcoholic fatty liver disease and steatohepatitis.
Aliment Pharmacol Ther
; 54(11-12): 1405-1415, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34671996
11.
Namodenoson in Advanced Hepatocellular Carcinoma and Child-Pugh B Cirrhosis: Randomized Placebo-Controlled Clinical Trial.
Cancers (Basel)
; 13(2)2021 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33430312
12.
Treatment of dry eye syndrome with orally administered CF101: data from a phase 2 clinical trial.
Ophthalmology
; 117(7): 1287-93, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20304499
13.
A phase 2, randomized, double-blind, placebo-controlled trial of clinical activity and safety of subcutaneous A6 in women with asymptomatic CA125 progression after first-line chemotherapy of epithelial ovarian cancer.
Gynecol Oncol
; 111(1): 89-94, 2008 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-18760451
14.
Inhibition of IL-17 and IL-23 in Human Keratinocytes by the A3 Adenosine Receptor Agonist Piclidenoson.
J Immunol Res
; 2018: 2310970, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29862305
15.
A phase I clinical trial of dTCApFs, a derivative of a novel human hormone peptide, for the treatment of advanced/metastatic solid tumors.
Mol Clin Oncol
; 8(1): 22-29, 2018 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-29423221
16.
A Proposed New Classification of Skin and Soft Tissue Infections Modeled on the Subset of Diabetic Foot Infection.
Open Forum Infect Dis
; 4(1): ofw255, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28480249
17.
Editorial: targeting aberrant hepatic inflammation for treatment of non-alcoholic steatohepatitis-authors' reply.
Aliment Pharmacol Ther
; 55(4): 485-486, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35092054
18.
Safety, tolerability and pharmacodynamics of a novel immunomodulator, MIS416, in patients with chronic progressive multiple sclerosis.
Mult Scler J Exp Transl Clin
; 1: 2055217315583385, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-28607691
19.
Continuous safety monitoring for randomized controlled clinical trials with blinded treatment information. Part 3: Design considerations.
Contemp Clin Trials
; 32 Suppl 1: S8-10, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21664988
20.
Continuous safety monitoring for randomized controlled clinical trials with blinded treatment information. Part 1: Ethical considerations.
Contemp Clin Trials
; 32 Suppl 1: S2-4, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21664987