Pesquisa | Secretaria de Estado da Saúde

1.

Pharmacokinetics and pharmacodynamics of the novel monobactam LYS228 in a neutropenic murine thigh model of infection.

Growcott, E J; Cariaga, T A; Morris, L; Zang, X; Lopez, S; Ansaldi, D A; Gold, J; Gamboa, L; Roth, T; Simmons, R L; Osborne, C S.

J Antimicrob Chemother ; 74(1): 108-116, 2019 01 01.

Artigo Inglês | MEDLINE | ID: mdl-30325447

2.

Pharmacokinetics and pharmacodynamics of the novel monobactam LYS228 in a neutropenic murine thigh model of infection.

Growcott, E J; Cariaga, T A; Morris, L; Zang, X; Lopez, S; Ansaldi, D A; Gold, J; Gamboa, L; Roth, T; Simmons, R L; Osborne, C S.

J Antimicrob Chemother ; 74(1): 280, 2019 01 01.

Artigo Inglês | MEDLINE | ID: mdl-30412250

3.

Differential effects of chlorpromazine on the in vitro generation and effector function of cytotoxic lymphocytes.

Ferguson, R M; Schmidtke, J R; Simmons, R L.

J Exp Med ; 143(1): 232-7, 1976 Jan 01.

Artigo Inglês | MEDLINE | ID: mdl-1244420

4.

Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells.

Curran, R D; Billiar, T R; Stuehr, D J; Hofmann, K; Simmons, R L.

J Exp Med ; 170(5): 1769-74, 1989 Nov 01.

Artigo Inglês | MEDLINE | ID: mdl-2509627

5.

An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro.

Billiar, T R; Curran, R D; Stuehr, D J; West, M A; Bentz, B G; Simmons, R L.

J Exp Med ; 169(4): 1467-72, 1989 Apr 01.

Artigo Inglês | MEDLINE | ID: mdl-2926330

6.

Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin.

Nussler, A K; Di Silvio, M; Billiar, T R; Hoffman, R A; Geller, D A; Selby, R; Madariaga, J; Simmons, R L.

J Exp Med ; 176(1): 261-4, 1992 Jul 01.

Artigo Inglês | MEDLINE | ID: mdl-1377225

7.

Immunotherapy of cancer: immunospecific rejection of tumors in recipients of neuraminidase-treated tumor cells plus BCG.

Simmons, R L; Rios, A.

Science ; 174(4009): 591-3, 1971 Nov 05.

Artigo Inglês | MEDLINE | ID: mdl-4940021

8.

Negative inotropic effects of cytokines on the heart mediated by nitric oxide.

Finkel, M S; Oddis, C V; Jacob, T D; Watkins, S C; Hattler, B G; Simmons, R L.

Science ; 257(5068): 387-9, 1992 Jul 17.

Artigo Inglês | MEDLINE | ID: mdl-1631560

9.

Hepatocellular transplantation for metabolic deficiencies: decrease of plasms bilirubin in Gunn rats.

Matas, A J; Sutherland, D E; Steffes, M W; Mauer, S M; Sowe, A; Simmons, R L; Najarian, J S.

Science ; 192(4242): 892-4, 1976 May 28.

Artigo Inglês | MEDLINE | ID: mdl-818706

10.

Antiserum to lymphocytes: prolonged survival of canine renal allografts.

Monaco, A P; Abbott, W M; Othersen, H B; Simmons, R L; Wood, M L; Flax, M H; Russell, P S.

Science ; 153(3741): 1264-7, 1966 Sep 09.

Artigo Inglês | MEDLINE | ID: mdl-5331415

11.

Nitric oxide production in host-versus-graft and graft-versus-host reactions in the rat.

Langrehr, J M; Murase, N; Markus, P M; Cai, X; Neuhaus, P; Schraut, W; Simmons, R L; Hoffman, R A.

J Clin Invest ; 90(2): 679-83, 1992 Aug.

Artigo Inglês | MEDLINE | ID: mdl-1379617

12.

Augmented uptake of neuraminidase-treated sheep red blood cells: participation of opsonic factors.

Schmidtke, J R; Simmons, R L.

J Natl Cancer Inst ; 54(6): 1379-84, 1975 Jun.

Artigo Inglês | MEDLINE | ID: mdl-48553

13.

Natural killer cell activity: age, estrous- and circadian-stage dependence and inverse correlation with metastatic potential.

Hrushesky, W J; Gruber, S A; Sothern, R B; Hoffman, R A; Lakatua, D; Carlson, A; Cerra, F; Simmons, R L.

J Natl Cancer Inst ; 80(15): 1232-7, 1988 Oct 05.

Artigo Inglês | MEDLINE | ID: mdl-3262168

14.

Increased circulating nitrogen oxides after human tumor immunotherapy: correlation with toxic hemodynamic changes.

Ochoa, J B; Curti, B; Peitzman, A B; Simmons, R L; Billiar, T R; Hoffman, R; Rault, R; Longo, D L; Urba, W J; Ochoa, A C.

J Natl Cancer Inst ; 84(11): 864-7, 1992 Jun 03.

Artigo Inglês | MEDLINE | ID: mdl-1375656

15.

Clinical spectrum of lymphoproliferative disorders in renal transplant recipients and evidence for the role of Epstein-Barr virus.

Hanto, D W; Frizzera, G; Purtilo, D T; Sakamoto, K; Sullivan, J L; Saemundsen, A K; Klein, G; Simmons, R L; Najarian, J S.

Cancer Res ; 41(11 Pt 1): 4253-61, 1981 Nov.

Artigo Inglês | MEDLINE | ID: mdl-6272971

16.

Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling.

Kim, Y M; Chung, H T; Kim, S S; Han, J A; Yoo, Y M; Kim, K M; Lee, G H; Yun, H Y; Green, A; Li, J; Simmons, R L; Billiar, T R.

J Neurosci ; 19(16): 6740-7, 1999 Aug 15.

Artigo Inglês | MEDLINE | ID: mdl-10436031

17.

Pregnancy in a juvenile diabetic after renal transplantation (class T diabetes mellitus).

Tagatz, G E; Arnold, N I; Goetz, F C; Najarian, J S; Simmons, R L.

Diabetes ; 24(5): 497-501, 1975 May.

Artigo Inglês | MEDLINE | ID: mdl-1092582

18.

Immunopathology of renal extracellular membranes in kidneys transplanted into patients with diabetes mellitus.

Mauer, S M; Miller, K; Goetz, F C; Barbosa, J; Simmons, R L; Najarian, J S; Michael, A F.

Diabetes ; 25(8): 709-12, 1976 Aug.

Artigo Inglês | MEDLINE | ID: mdl-782983

19.

Lipopolysaccharide binding protein participation in cellular activation by LPS.

Su, G L; Simmons, R L; Wang, S C.

Crit Rev Immunol ; 15(3-4): 201-14, 1995.

Artigo Inglês | MEDLINE | ID: mdl-8834448

20.

Cyclic GMP and guanylate cyclase mediate lipopolysaccharide-induced Kupffer cell tumor necrosis factor-alpha synthesis.

Harbrecht, B G; Wang, S C; Simmons, R L; Billiar, T R.

J Leukoc Biol ; 57(2): 297-302, 1995 Feb.

Artigo Inglês | MEDLINE | ID: mdl-7852845

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Pharmacokinetics and pharmacodynamics of the novel monobactam LYS228 in a neutropenic murine thigh model of infection.

Pharmacokinetics and pharmacodynamics of the novel monobactam LYS228 in a neutropenic murine thigh model of infection.

Differential effects of chlorpromazine on the in vitro generation and effector function of cytotoxic lymphocytes.

Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells.

An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro.

Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin.

Immunotherapy of cancer: immunospecific rejection of tumors in recipients of neuraminidase-treated tumor cells plus BCG.

Negative inotropic effects of cytokines on the heart mediated by nitric oxide.

Hepatocellular transplantation for metabolic deficiencies: decrease of plasms bilirubin in Gunn rats.

Antiserum to lymphocytes: prolonged survival of canine renal allografts.

Nitric oxide production in host-versus-graft and graft-versus-host reactions in the rat.

Augmented uptake of neuraminidase-treated sheep red blood cells: participation of opsonic factors.

Natural killer cell activity: age, estrous- and circadian-stage dependence and inverse correlation with metastatic potential.

Increased circulating nitrogen oxides after human tumor immunotherapy: correlation with toxic hemodynamic changes.

Clinical spectrum of lymphoproliferative disorders in renal transplant recipients and evidence for the role of Epstein-Barr virus.

Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling.

Pregnancy in a juvenile diabetic after renal transplantation (class T diabetes mellitus).

Immunopathology of renal extracellular membranes in kidneys transplanted into patients with diabetes mellitus.

Lipopolysaccharide binding protein participation in cellular activation by LPS.

Cyclic GMP and guanylate cyclase mediate lipopolysaccharide-induced Kupffer cell tumor necrosis factor-alpha synthesis.