Detalhe da pesquisa
1.
The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Mol Cell
; 81(6): 1170-1186.e10, 2021 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33571422
2.
Author Correction: Consistent success in life-supporting porcine cardiac xenotransplantation.
Nature
; 568(7752): E7, 2019 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-30944481
3.
Site-Selective Protein Conjugation by a Multicomponent Ugi Reaction.
Chemistry
; 30(14): e202303242, 2024 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38050774
4.
Consistent success in life-supporting porcine cardiac xenotransplantation.
Nature
; 564(7736): 430-433, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30518863
5.
Structural and Functional Analysis of a Highly Active Designed Phosphotriesterase for the Detoxification of Organophosphate Nerve Agents Reveals an Unpredicted Conformation of the Active Site Loop.
Biochemistry
; 62(4): 942-955, 2023 02 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36752589
6.
Engineered Protein Scaffolds as Next-Generation Therapeutics.
Annu Rev Pharmacol Toxicol
; 60: 391-415, 2020 01 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31914898
7.
FerryCalin: an Engineered Lipocalin Protein Directed against the Transferrin Receptor with Potential for Brain Drug Delivery.
Chembiochem
; 24(10): e202200795, 2023 05 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37005222
8.
cART Restores Transient Responsiveness to IFN Type 1 in HIV-Infected Humanized Mice.
J Virol
; 96(21): e0082722, 2022 11 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36250708
9.
Complement inhibition at the level of C3 or C5: mechanistic reasons for ongoing terminal pathway activity.
Blood
; 137(4): 443-455, 2021 01 28.
Artigo
Inglês
| MEDLINE | ID: mdl-33507296
10.
Molecular Design of 68Ga- and 89Zr-Labeled Anticalin Radioligands for PET-Imaging of PSMA-Positive Tumors.
Mol Pharm
; 20(5): 2490-2501, 2023 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37068305
11.
Structural basis of Alzheimer ß-amyloid peptide recognition by engineered lipocalin proteins with aggregation-blocking activity.
Biol Chem
; 403(5-6): 557-571, 2022 04 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35355502
12.
Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel.
Nat Immunol
; 11(9): 814-9, 2010 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-20711192
13.
Post-VX exposure treatment of rats with engineered phosphotriesterases.
Arch Toxicol
; 96(2): 571-583, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34962578
14.
Direct Affinity Purification of Long-Acting PASylated Proteins with Therapeutic Potential Using L-Prolinamide for Mild Elution.
Angew Chem Int Ed Engl
; 61(25): e202200079, 2022 06 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35325504
15.
PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis.
J Biol Chem
; 295(3): 868-882, 2020 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-31819009
16.
The extracellular region of bovine milk butyrophilin exhibits closer structural similarity to human myelin oligodendrocyte glycoprotein than to immunological BTN family receptors.
Biol Chem
; 402(10): 1187-1202, 2021 09 27.
Artigo
Inglês
| MEDLINE | ID: mdl-34342946
17.
Catalytic activity and stereoselectivity of engineered phosphotriesterases towards structurally different nerve agents in vitro.
Arch Toxicol
; 95(8): 2815-2823, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34160649
18.
Translating the Concept of Bispecific Antibodies to Engineering Heterodimeric Phosphotriesterases with Broad Organophosphate Substrate Recognition.
Biochemistry
; 59(45): 4395-4406, 2020 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33146522
19.
Scavenging Bacterial Siderophores with Engineered Lipocalin Proteins as an Alternative Antimicrobial Strategy.
Chembiochem
; 21(5): 601-606, 2020 03 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31613035
20.
A Tetrahedral Boronic Acid Diester Formed by an Unnatural Amino Acid in the Ligand Pocket of an Engineered Lipocalin.
Chembiochem
; 21(4): 469-472, 2020 02 17.
Artigo
Inglês
| MEDLINE | ID: mdl-31390134