Detalhe da pesquisa
1.
Biomechanical interactions of Schistosoma mansoni eggs with vascular endothelial cells facilitate egg extravasation.
PLoS Pathog
; 18(3): e1010309, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35316298
2.
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2.
J Chem Inf Model
; 62(24): 6553-6573, 2022 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35960688
3.
Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone.
J Antimicrob Chemother
; 75(10): 2925-2932, 2020 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32617557
4.
Developmental Sensitivity in Schistosoma mansoni to Puromycin To Establish Drug Selection of Transgenic Schistosomes.
Antimicrob Agents Chemother
; 62(8)2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29760143
5.
Pseudotyped murine leukemia virus for schistosome transgenesis: approaches, methods and perspectives.
Transgenic Res
; 23(3): 539-56, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24474164
6.
Development of subunit selective proteasome substrates for Schistosoma species.
bioRxiv
; 2024 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38405969
7.
Structure-based discovery of thiosemicarbazones as SARS-CoV-2 main protease inhibitors.
Future Med Chem
; 15(11): 959-985, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37435731
8.
Discovery of Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L.
Pharmaceuticals (Basel)
; 15(6)2022 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-35745663
9.
Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L.
J Med Chem
; 65(4): 2956-2970, 2022 02 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34730959
10.
Structure-based identification of naphthoquinones and derivatives as novel inhibitors of main protease Mpro and papain-like protease PLpro of SARS-CoV-2.
bioRxiv
; 2022 Jan 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35018373
11.
Progress with schistosome transgenesis.
Mem Inst Oswaldo Cruz
; 106(7): 785-93, 2011 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22124549
12.
A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules.
ACS Infect Dis
; 7(2): 406-420, 2021 02 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33434015
13.
Congeners Derived from Microtubule-Active Phenylpyrimidines Produce a Potent and Long-Lasting Paralysis of Schistosoma mansoni In Vitro.
ACS Infect Dis
; 7(5): 1089-1103, 2021 05 14.
Artigo
Inglês
| MEDLINE | ID: mdl-33135408
14.
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells.
ACS Chem Biol
; 16(4): 642-650, 2021 04 16.
Artigo
Inglês
| MEDLINE | ID: mdl-33787221
15.
Functional analysis of vasa/PL10-like genes in the ovary of Schistosoma mansoni.
Mol Biochem Parasitol
; 236: 111259, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31958469
16.
Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty.
Pharmaceuticals (Basel)
; 13(2)2020 02 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32028743
17.
Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L.
bioRxiv
; 2020 Dec 24.
Artigo
Inglês
| MEDLINE | ID: mdl-33398273
18.
A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells.
bioRxiv
; 2020 Oct 30.
Artigo
Inglês
| MEDLINE | ID: mdl-33140046
19.
Bioactivity of Farnesyltransferase Inhibitors Against Entamoeba histolytica and Schistosoma mansoni.
Front Cell Infect Microbiol
; 9: 180, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31192168
20.
Quantifying the mechanics of locomotion of the schistosome pathogen with respect to changes in its physical environment.
J R Soc Interface
; 16(150): 20180675, 2019 01 31.
Artigo
Inglês
| MEDLINE | ID: mdl-30958153