Detalhe da pesquisa
1.
Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis.
Development
; 141(7): 1465-72, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24598168
2.
Reticulon 4 is necessary for endoplasmic reticulum tubulation, STIM1-Orai1 coupling, and store-operated calcium entry.
J Biol Chem
; 289(13): 9380-95, 2014 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-24558039
3.
PF-1355, a mechanism-based myeloperoxidase inhibitor, prevents immune complex vasculitis and anti-glomerular basement membrane glomerulonephritis.
J Pharmacol Exp Ther
; 353(2): 288-98, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25698787
4.
Inhibition of lysine acetyltransferase KAT6 in ER+HER2- metastatic breast cancer: a phase 1 trial.
Nat Med
; 2024 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38824244
5.
Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial.
Nat Med
; 29(10): 2570-2576, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37783970
6.
Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis.
Arterioscler Thromb Vasc Biol
; 31(1): 81-5, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20947824
7.
MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function.
Arterioscler Thromb Vasc Biol
; 30(6): 1118-26, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20378849
8.
Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina.
J Clin Invest
; 117(9): 2506-16, 2007 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-17710232
9.
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN.
Arterioscler Thromb Vasc Biol
; 27(6): 1312-8, 2007 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-17431187
10.
2-Aminopyridine-Based Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Inhibitors: Assessment of Mechanism-Based Safety.
J Med Chem
; 61(7): 3114-3125, 2018 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29570292
11.
Myeloperoxidase Inhibition Improves Ventricular Function and Remodeling After Experimental Myocardial Infarction.
JACC Basic Transl Sci
; 1(7): 633-643, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-30167547
12.
Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis.
Nat Commun
; 6: 8995, 2015 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-26688060
13.
Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment.
ACS Med Chem Lett
; 6(11): 1128-33, 2015 Nov 12.
Artigo
Inglês
| MEDLINE | ID: mdl-26617966
14.
Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development.
Dev Cell
; 23(3): 600-10, 2012 Sep 11.
Artigo
Inglês
| MEDLINE | ID: mdl-22975328
15.
Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function.
PLoS One
; 6(4): e18869, 2011 Apr 22.
Artigo
Inglês
| MEDLINE | ID: mdl-21526127
16.
Lysophospholipid receptors in vertebrate development, physiology, and pathology.
J Lipid Res
; 50 Suppl: S293-8, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19065000
17.
Regulation of vascular physiology and pathology by the S1P2 receptor subtype.
Cardiovasc Res
; 82(2): 221-8, 2009 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19287048
18.
Deafness and stria vascularis defects in S1P2 receptor-null mice.
J Biol Chem
; 282(14): 10690-6, 2007 Apr 06.
Artigo
Inglês
| MEDLINE | ID: mdl-17284444
19.
Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization.
Genes Dev
; 18(19): 2392-403, 2004 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15371328