Detalhe da pesquisa
1.
Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.
Nat Immunol
; 19(12): 1299-1308, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30374129
2.
A Randomized Controlled Clinical Trial of Nasal Immunization with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge.
Am J Respir Crit Care Med
; 208(8): 868-878, 2023 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37556679
3.
Human Infection Challenge with Serotype 3 Pneumococcus.
Am J Respir Crit Care Med
; 206(11): 1379-1392, 2022 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35802840
4.
Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.
Am J Respir Crit Care Med
; 201(3): 335-347, 2020 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31626559
5.
Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.
Respir Res
; 19(1): 66, 2018 04 18.
Artigo
Inglês
| MEDLINE | ID: mdl-29669565
6.
Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage.
Am J Respir Crit Care Med
; 194(12): 1523-1531, 2016 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27403678
7.
Serotype 3 Experimental Human Pneumococcal Challenge (EHPC) study protocol: dose ranging and reproducibility in a healthy volunteer population (challenge 3).
BMJ Open
; 14(1): e075948, 2024 01 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38199622
8.
Surveillance towards preventing paediatric incidence of respiratory syncytial virus attributable respiratory tract infection in primary and secondary/tertiary healthcare settings in Merseyside, Cheshire and Bristol, UK.
BMJ Open Respir Res
; 10(1)2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37277188
9.
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination.
Nat Commun
; 14(1): 6815, 2023 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-37884506
10.
Detection of SARS-CoV-2 infection by saliva and nasopharyngeal sampling in frontline healthcare workers: An observational cohort study.
PLoS One
; 18(1): e0280908, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36706119
11.
Influence of sex, season and environmental air quality on experimental human pneumococcal carriage acquisition: a retrospective cohort analysis.
ERJ Open Res
; 8(2)2022 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-35415189
12.
Association between household air pollution and nasopharyngeal pneumococcal carriage in Malawian infants (MSCAPE): a nested, prospective, observational study.
Lancet Glob Health
; 10(2): e246-e256, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35063113
13.
Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccharide vaccine on pneumococcal colonisation using the experimental human pneumococcal challenge model in healthy adults (PREVENTING PNEUMO 2).
BMJ Open
; 12(7): e062109, 2022 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35798520
14.
Streptococcus pneumoniae colonization associates with impaired adaptive immune responses against SARS-CoV-2.
J Clin Invest
; 132(7)2022 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35139037
15.
Evaluation of polymer choice on immunogenicity of chitosan coated PLGA NPs with surface-adsorbed pneumococcal protein antigen PspA4Pro.
Int J Pharm
; 599: 120407, 2021 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33675930
16.
Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine.
JCI Insight
; 6(4)2021 02 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33497364
17.
Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults.
mBio
; 12(1)2021 01 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33436429
18.
The nose is the best niche for detection of experimental pneumococcal colonisation in adults of all ages, using nasal wash.
Sci Rep
; 11(1): 18279, 2021 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34521967
19.
Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus.
Nat Microbiol
; 5(7): 909-916, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32313202
20.
Symptoms associated with influenza vaccination and experimental human pneumococcal colonisation of the nasopharynx.
Vaccine
; 38(10): 2298-2306, 2020 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-32035708