Detalhe da pesquisa
1.
Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance.
Genome Res
; 29(9): 1442-1452, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31467027
2.
Down-regulation of TNF-α via macrophage-targeted RNAi system for the treatment of acute inflammatory sepsis.
J Control Release
; 336: 344-353, 2021 08 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34147573
3.
White adipocyte-targeted dual gene silencing of FABP4/5 for anti-obesity, anti-inflammation and reversal of insulin resistance: Efficacy and comparison of administration routes.
Biomaterials
; 279: 121209, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34700224
4.
RNA interference-mediated suppression of TNF-α converting enzyme as an alternative anti-TNF-α therapy for rheumatoid arthritis.
J Control Release
; 330: 1300-1312, 2021 02 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33242532
5.
Non-viral nano-immunotherapeutics targeting tumor microenvironmental immune cells.
Biomaterials
; 219: 119401, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31398571
6.
Recent challenges and advances in genetically-engineered cell therapy.
J Pharm Investig
; 48(2): 199-208, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30680249
7.
Visceral adipose tissue macrophage-targeted TACE silencing to treat obesity-induced type 2 diabetes.
Biomaterials
; 148: 81-89, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-28985514
8.
Mononuclear phagocytes as a target, not a barrier, for drug delivery.
J Control Release
; 259: 53-61, 2017 08 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28108325
9.
RNAi-mediated silencing of TNF-α converting enzyme to down-regulate soluble TNF-α production for treatment of acute and chronic colitis.
J Control Release
; 239: 231-41, 2016 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27562600