Detalhe da pesquisa
1.
Biological Diagnosis of Alzheimer's Disease Based on Amyloid Status: An Illustration of Confirmation Bias in Medical Research?
Int J Mol Sci
; 24(24)2023 Dec 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38139372
2.
ßAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer's Disease.
Cereb Cortex
; 28(11): 3976-3993, 2018 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29048465
3.
Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice.
Brain
; 140(3): 826-842, 2017 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28003243
4.
Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a.
J Neurosci
; 34(4): 1138-47, 2014 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24453307
5.
Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.
Neurobiol Dis
; 69: 65-75, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24801365
6.
DYRK1A: a master regulatory protein controlling brain growth.
Neurobiol Dis
; 46(1): 190-203, 2012 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-22293606
7.
Real-Time Monitoring of Exosome Enveloped-AAV Spreading by Endomicroscopy Approach: A New Tool for Gene Delivery in the Brain.
Mol Ther Methods Clin Dev
; 14: 237-251, 2019 Sep 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31440523
8.
Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models.
Sci Rep
; 9(1): 3914, 2019 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30850713
9.
Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice.
Acta Neuropathol Commun
; 7(1): 46, 2019 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30885273
10.
Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues.
Mol Neurobiol
; 55(5): 3822-3831, 2018 May.
Artigo
Inglês
| MEDLINE | ID: mdl-28540658
11.
Specific age-related molecular alterations in the cerebellum of Down syndrome mouse models.
Brain Res
; 1646: 342-353, 2016 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27297494
12.
Molecular rescue of DYRK1A overexpression in cystathionine beta synthase-deficient mouse brain by enriched environment combined with voluntary exercise.
J Mol Neurosci
; 55(2): 318-23, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24819931
13.
Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models.
Front Behav Neurosci
; 9: 267, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26539088
14.
Is it time to rethink the Alzheimer's disease drug development strategy by targeting its silent phase?
Neural Regen Res
; 13(2): 224-225, 2018 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-29557364