Detalhe da pesquisa
1.
High-Throughput Discovery and Characterization of Human Transcriptional Effectors.
Cell
; 183(7): 2020-2035.e16, 2020 12 23.
Artigo
Inglês
| MEDLINE | ID: mdl-33326746
2.
Large-scale mapping and mutagenesis of human transcriptional effector domains.
Nature
; 616(7956): 365-372, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37020022
3.
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis.
Nature
; 597(7877): 549-554, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34497417
4.
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.
Nature
; 580(7801): 136-141, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32238925
5.
SLC12A9 is a lysosome-detoxifying ammonium - chloride co-transporter.
bioRxiv
; 2023 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37292735
6.
An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation.
Sci Adv
; 9(16): eadf8966, 2023 04 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37075117
7.
High-throughput functional characterization of combinations of transcriptional activators and repressors.
Cell Syst
; 14(9): 746-763.e5, 2023 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37543039
8.
Death-seq identifies regulators of cell death and senolytic therapies.
Cell Metab
; 35(10): 1814-1829.e6, 2023 10 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37699398
9.
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes.
Nat Genet
; 53(5): 638-649, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33859415
10.
Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities.
Cancer Discov
; 10(12): 1950-1967, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32727735
11.
Genetic variation drives seasonal onset of hibernation in the 13-lined ground squirrel.
Commun Biol
; 2: 478, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31886416
12.
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements.
Nat Commun
; 10(1): 4063, 2019 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31492858