Detalhe da pesquisa
1.
Signal Propagation in the ATPase Domain of Mycobacterium tuberculosis DNA Gyrase from Dynamical-Nonequilibrium Molecular Dynamics Simulations.
Biochemistry
; 2024 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38742407
2.
Interactions of hydrolyzed ß-lactams with the L1 metallo-ß-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products.
J Biol Chem
; 299(5): 104606, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36924941
3.
The Ableist stare: an interdisciplinary, narrative-driven exploration of staring at disabled bodies.
Med Humanit
; 2024 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38378267
4.
Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 ß-Lactamase.
J Am Chem Soc
; 145(13): 7166-7180, 2023 04 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36972204
5.
Discovering Quantum Phase Transitions with Fermionic Neural Networks.
Phys Rev Lett
; 130(3): 036401, 2023 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36763402
6.
Bioisosteric Design Identifies Inhibitors of Mycobacterium tuberculosis DNA Gyrase ATPase Activity.
J Chem Inf Model
; 63(9): 2707-2718, 2023 05 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37074047
7.
Enhancement by pyrazolones of colistin efficacy against mcr-1-expressing E. coli: an in silico and in vitro investigation.
J Comput Aided Mol Des
; 37(10): 479-489, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37488458
8.
Postoperative Delirium Severity and Recovery Correlate With Electroencephalogram Spectral Features.
Anesth Analg
; 136(1): 140-151, 2023 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36130079
9.
Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl-enzyme conformational dynamics to extend antibiotic resistance.
J Biol Chem
; 296: 100126, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33257320
10.
A multiscale approach to predict the binding mode of metallo beta-lactamase inhibitors.
Proteins
; 90(2): 372-384, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34455628
11.
Inhibition of Mycobacterium tuberculosis InhA by 3-nitropropanoic acid.
Proteins
; 90(3): 898-904, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34677871
12.
Identification of Potent DNA Gyrase Inhibitors Active against Mycobacterium tuberculosis.
J Chem Inf Model
; 62(7): 1680-1690, 2022 04 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35347987
13.
Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity.
J Chem Inf Model
; 62(24): 6508-6518, 2022 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35994014
14.
Cladobotric Acids: Metabolites from Cultures of Cladobotryum sp., Semisynthetic Analogues and Antibacterial Activity.
J Nat Prod
; 85(3): 572-580, 2022 03 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35170975
15.
Tumour treating fields therapy for glioblastoma: current advances and future directions.
Br J Cancer
; 124(4): 697-709, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33144698
16.
Antimicrobial Resistance Conferred by OXA-48 ß-Lactamases: Towards a Detailed Mechanistic Understanding.
Antimicrob Agents Chemother
; 65(6)2021 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33753332
17.
Catalytic mechanism of the colistin resistance protein MCR-1.
Org Biomol Chem
; 19(17): 3813-3819, 2021 05 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33606866
18.
Crystallography and QM/MM Simulations Identify Preferential Binding of Hydrolyzed Carbapenem and Penem Antibiotics to the L1 Metallo-ß-Lactamase in the Imine Form.
J Chem Inf Model
; 61(12): 5988-5999, 2021 12 27.
Artigo
Inglês
| MEDLINE | ID: mdl-34637298
19.
Multiscale Workflow for Modeling Ligand Complexes of Zinc Metalloproteins.
J Chem Inf Model
; 61(11): 5658-5672, 2021 11 22.
Artigo
Inglês
| MEDLINE | ID: mdl-34748329
20.
A landscape planning agenda for global health security: Learning from the history of HIV/AIDS and pandemic influenza.
Landsc Urban Plan
; 216: 104242, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-36536764