RESUMO
Data are presented on the results of photodynamic treatment (PDT) of mice DBA2 with transplantable lympho-leukemia P-388. Different regimens of photosensitizer Dimegin and emission were used. Both intravenous PDT and in combination with local PDT should be recommended.
Assuntos
Deuteroporfirinas/uso terapêutico , Leucemia Experimental/tratamento farmacológico , Linfoma/tratamento farmacológico , Fármacos Fotossensibilizantes/uso terapêutico , Animais , Camundongos , Camundongos Endogâmicos DBA , Neoplasias Experimentais/tratamento farmacológico , Fotoquimioterapia/instrumentação , Fotoquimioterapia/métodos , Transplante Heterólogo , Resultado do TratamentoRESUMO
Biological effects of Lamipharen treatment of sarcoma M-1 was studied in newborn rats and photodynamic therapy in combination with radiation was evaluated.
Assuntos
Terapia com Luz de Baixa Intensidade , Fotoquimioterapia , Fármacos Fotossensibilizantes/uso terapêutico , Sarcoma Experimental/tratamento farmacológico , Animais , Animais Recém-Nascidos , Fotoquimioterapia/efeitos adversos , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes/administração & dosagem , Fármacos Fotossensibilizantes/efeitos adversos , Radioterapia Adjuvante , Ratos , Ratos Wistar , Sarcoma Experimental/radioterapiaRESUMO
Interaction between such components of photodynamic therapy as tumor, intact tissues, lighting and photosensitizers has been investigated. The efficacy of Photosense treatment was demonstrated in the experiments using transplantable tumors in Wistar rats. The photodynamic procedure both inhibited tumor process and stimulated immune system.