Detalhe da pesquisa
1.
K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.
Nat Immunol
; 15(3): 231-8, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24464131
2.
Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells.
PLoS Pathog
; 19(11): e1011842, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-38033162
3.
Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking.
Proc Natl Acad Sci U S A
; 119(39): e2204396119, 2022 09 27.
Artigo
Inglês
| MEDLINE | ID: mdl-36122218
4.
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis.
J Lipid Res
; 65(6): 100556, 2024 May 06.
Artigo
Inglês
| MEDLINE | ID: mdl-38719150
5.
Sphingosine-1-phosphate and its receptors in vascular endothelial and lymphatic barrier function.
J Biol Chem
; 299(6): 104775, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37142226
6.
Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice.
FASEB J
; 37(3): e22799, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36753412
7.
A new preclinical model of western diet-induced progression of non-alcoholic steatohepatitis to hepatocellular carcinoma.
FASEB J
; 36(7): e22372, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35639028
8.
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization.
Nature
; 541(7636): 233-236, 2017 01 12.
Artigo
Inglês
| MEDLINE | ID: mdl-28052056
9.
Neuronal contact upregulates astrocytic sphingosine-1-phosphate receptor 1 to coordinate astrocyte-neuron cross communication.
Glia
; 70(4): 712-727, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34958493
10.
Deletion or inhibition of SphK1 mitigates fulminant hepatic failure by suppressing TNFα-dependent inflammation and apoptosis.
FASEB J
; 35(3): e21415, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33566377
11.
Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain.
Proc Natl Acad Sci U S A
; 116(21): 10557-10562, 2019 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31068460
12.
Ceramide in apoptosis and oxidative stress in allergic inflammation and asthma.
J Allergy Clin Immunol
; 147(5): 1936-1948.e9, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33130063
13.
CRISPR/Cas9 deletion of ORMDLs reveals complexity in sphingolipid metabolism.
J Lipid Res
; 62: 100082, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33939982
14.
Sphingosine-1-phosphate: From insipid lipid to a key regulator.
J Biol Chem
; 295(10): 3371-3384, 2020 03 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32144147
15.
Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.
J Biol Chem
; 295(27): 9121-9133, 2020 07 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32385114
16.
Regulatory role of SphK1 in TLR7/9-dependent type I interferon response and autoimmunity.
FASEB J
; 34(3): 4329-4347, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31971297
17.
Tumor-derived exosomes (TDEs): How to avoid the sting in the tail.
Med Res Rev
; 40(1): 385-412, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31318078
18.
A simple method for sphingolipid analysis of tissues embedded in optimal cutting temperature compound.
J Lipid Res
; 61(6): 953-967, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32341007
19.
Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents.
J Neuroinflammation
; 17(1): 314, 2020 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33092620
20.
Examination of the role of sphingosine kinase 2 in a murine model of systemic lupus erythematosus.
FASEB J
; 33(6): 7061-7071, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30840833