Detalhe da pesquisa
1.
Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.
Cell
; 184(9): 2454-2470.e26, 2021 04 29.
Artigo
Inglês
| MEDLINE | ID: mdl-33857425
2.
DNMT3B PWWP mutations cause hypermethylation of heterochromatin.
EMBO Rep
; 25(3): 1130-1155, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38291337
3.
Genome-wide single-molecule analysis of long-read DNA methylation reveals heterogeneous patterns at heterochromatin that reflect nucleosome organisation.
PLoS Genet
; 19(10): e1010958, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37782664
4.
Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators.
Genes Dev
; 31(8): 757-773, 2017 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28465359
5.
An epigenetic predictor of death captures multi-modal measures of brain health.
Mol Psychiatry
; 26(8): 3806-3816, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31796892
6.
Activation of transcription factor circuity in 2i-induced ground state pluripotency is independent of repressive global epigenetic landscapes.
Nucleic Acids Res
; 48(14): 7748-7766, 2020 08 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32585002
7.
Variable outcome and methylation status according to CEBPA mutant type in double-mutated acute myeloid leukemia patients and the possible implications for treatment.
Haematologica
; 103(1): 91-100, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29025912
8.
Analysis of active and inactive X chromosome architecture reveals the independent organization of 30 nm and large-scale chromatin structures.
Mol Cell
; 40(3): 397-409, 2010 Nov 12.
Artigo
Inglês
| MEDLINE | ID: mdl-21070966
9.
Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination.
Mol Cell
; 38(3): 452-64, 2010 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-20471950
10.
Transcription factor binding predicts histone modifications in human cell lines.
Proc Natl Acad Sci U S A
; 111(37): 13367-72, 2014 Sep 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25187560
11.
DNA methylation reprogramming in cancer: does it act by re-configuring the binding landscape of Polycomb repressive complexes?
Bioessays
; 36(2): 134-40, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24277643
12.
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes.
Genome Res
; 22(3): 467-77, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22106369
13.
Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer.
Nucleic Acids Res
; 41(14): 6857-69, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23703216
14.
Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression.
Nucleic Acids Res
; 40(11): 4794-803, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-22323521
15.
Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer.
Proc Natl Acad Sci U S A
; 108(11): 4364-9, 2011 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21368160
16.
Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair.
Nat Commun
; 14(1): 3636, 2023 06 19.
Artigo
Inglês
| MEDLINE | ID: mdl-37336879
17.
Cluster mean-field theory accurately predicts statistical properties of large-scale DNA methylation patterns.
J R Soc Interface
; 19(186): 20210707, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35078341
18.
Local CpG density affects the trajectory and variance of age-associated DNA methylation changes.
Genome Biol
; 23(1): 216, 2022 10 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36253871
19.
In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma.
Cancer Res
; 82(8): 1548-1559, 2022 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35074757
20.
Modelling genetic and clinical heterogeneity in epithelial ovarian cancers.
Carcinogenesis
; 32(10): 1540-9, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21859834