Detalhe da pesquisa
1.
Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells.
Immunity
; 51(5): 856-870.e5, 2019 11 19.
Artigo
Inglês
| MEDLINE | ID: mdl-31747582
2.
A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.
J Inherit Metab Dis
; 39(6): 807-820, 2016 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27469509
3.
13C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8+ T cells.
bioRxiv
; 2023 Jun 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37333111
4.
Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase.
Mol Cancer Ther
; 19(12): 2502-2515, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33082276
5.
Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.
Cell Metab
; 31(2): 250-266.e9, 2020 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32023446
6.
JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.
J Clin Invest
; 128(2): 789-804, 2018 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29355841
7.
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.
Nat Med
; 24(8): 1192-1203, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29988124
8.
The mitochondrial respiratory chain is essential for haematopoietic stem cell function.
Nat Cell Biol
; 19(6): 614-625, 2017 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-28504706
9.
Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition.
PLoS One
; 9(12): e115144, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-25502225
10.
JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.
J Clin Invest
; 128(10): 4743, 2018 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30222137