Detalhe da pesquisa
1.
Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Mol Cell
; 84(7): 1304-1320.e16, 2024 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38382526
2.
Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol Cell
; 83(2): 167-185.e9, 2023 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-36577401
3.
Nuclear mRNPs are compact particles packaged with a network of proteins promoting RNA-RNA interactions.
Genes Dev
; 37(11-12): 505-517, 2023 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37399331
4.
Structure of the human signal peptidase complex reveals the determinants for signal peptide cleavage.
Mol Cell
; 81(19): 3934-3948.e11, 2021 10 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34388369
5.
Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding.
EMBO J
; 40(15): e107807, 2021 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34191293
6.
Efficient Tandem Copper-Catalyzed Click Synthesis of Multisugar-Modified Oligonucleotides.
Angew Chem Int Ed Engl
; : e202405161, 2024 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38606873
7.
Synthesis and Structure Elucidation of Glutamyl-Queuosine.
J Am Chem Soc
; 145(47): 25528-25532, 2023 11 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37967838
8.
Benefits of Collisional Cross Section Assisted Precursor Selection (caps-PASEF) for Cross-linking Mass Spectrometry.
Mol Cell Proteomics
; 19(10): 1677-1687, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32694122
9.
Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
Nat Chem Biol
; 10(7): 574-81, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24838012
10.
Synthesis of a DNA promoter segment containing all four epigenetic nucleosides: 5-methyl-, 5-hydroxymethyl-, 5-formyl-, and 5-carboxy-2'-deoxycytidine.
Angew Chem Int Ed Engl
; 53(1): 315-8, 2014 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24281791
11.
Long-lived proteins and DNA as candidate predictive biomarkers for tissue associated diseases.
iScience
; 27(4): 109642, 2024 Apr 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38632996
12.
Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination.
Nat Commun
; 15(1): 2890, 2024 Apr 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38570537
13.
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.
Nat Struct Mol Biol
; 2024 Apr 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38605244
14.
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases.
Nat Struct Mol Biol
; 31(2): 378-389, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38326650
15.
Deamination, oxidation, and C-C bond cleavage reactivity of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine.
J Am Chem Soc
; 135(39): 14593-9, 2013 Oct 02.
Artigo
Inglês
| MEDLINE | ID: mdl-23980549
16.
Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment.
Nat Commun
; 14(1): 6814, 2023 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-37884489
17.
Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation.
Nat Commun
; 13(1): 3041, 2022 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35650207
18.
Fishing for newly synthesized proteins with phosphonate-handles.
Nat Commun
; 11(1): 3244, 2020 06 26.
Artigo
Inglês
| MEDLINE | ID: mdl-32591520
19.
PhoX: An IMAC-Enrichable Cross-Linking Reagent.
ACS Cent Sci
; 5(9): 1514-1522, 2019 Sep 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31572778
20.
Efficient and robust proteome-wide approaches for cross-linking mass spectrometry.
Nat Protoc
; 13(12): 2964-2990, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30446747