Detalhe da pesquisa
1.
The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier.
Cell
; 176(3): 435-447.e15, 2019 01 24.
Artigo
Inglês
| MEDLINE | ID: mdl-30611538
2.
Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Cell
; 172(1-2): 55-67.e15, 2018 01 11.
Artigo
Inglês
| MEDLINE | ID: mdl-29307491
3.
Structure, mechanism, and inhibition of Hedgehog acyltransferase.
Mol Cell
; 81(24): 5025-5038.e10, 2021 12 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34890564
4.
Structural basis of sodium-dependent bile salt uptake into the liver.
Nature
; 606(7916): 1015-1020, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35545671
5.
Structure, substrate recognition and initiation of hyaluronan synthase.
Nature
; 604(7904): 195-201, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35355017
6.
Author Correction: Structural insights into µ-opioid receptor activation.
Nature
; 584(7820): E16, 2020 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-32724208
7.
Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
Proc Natl Acad Sci U S A
; 120(41): e2300258120, 2023 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37801475
8.
Cryo-EM structure of the human α1ß3γ2 GABAA receptor in a lipid bilayer.
Nature
; 565(7740): 516-520, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30602789
9.
Author Correction: GABAA receptor signalling mechanisms revealed by structural pharmacology.
Nature
; 566(7744): E8, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30733619
10.
Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature
; 573(7773): 287-290, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31485076
11.
GABAA receptor signalling mechanisms revealed by structural pharmacology.
Nature
; 565(7740): 454-459, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30602790
12.
Author Correction: Structural insights into the activation of metabotropic glutamate receptors.
Nature
; 567(7747): E10, 2019 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-30814739
13.
Structural insights into the activation of metabotropic glutamate receptors.
Nature
; 566(7742): 79-84, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30675062
14.
Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2.
Proc Natl Acad Sci U S A
; 119(9)2022 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35217606
15.
In vivo and in vitro characterizations of melibiose permease (MelB) conformation-dependent nanobodies reveal sugar-binding mechanisms.
J Biol Chem
; 299(8): 104967, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37380079
16.
Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Nat Methods
; 18(1): 60-68, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33408403
17.
Structures of ß-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.
Nature
; 553(7689): 501-505, 2018 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-29342135
18.
Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Proc Natl Acad Sci U S A
; 118(47)2021 11 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34782475
19.
Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation.
Proc Natl Acad Sci U S A
; 118(33)2021 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34385319
20.
A topological switch in CFTR modulates channel activity and sensitivity to unfolding.
Nat Chem Biol
; 17(9): 989-997, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34341587