Detalhe da pesquisa
1.
Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial.
Lancet
; 393(10184): 1948-1957, 2019 05 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30982686
2.
Maintenance strategies after first-line oxaliplatin plus fluoropyrimidine plus bevacizumab for patients with metastatic colorectal cancer (AIO 0207): a randomised, non-inferiority, open-label, phase 3 trial.
Lancet Oncol
; 16(13): 1355-69, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26361971
3.
Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial.
Lancet Oncol
; 11(1): 38-47, 2010 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19942479
4.
Microsatellite instability (MSI-H) is associated with a high immunoscore but not with PD-L1 expression or increased survival in patients (pts.) with metastatic colorectal cancer (mCRC) treated with oxaliplatin (ox) and fluoropyrimidine (FP) with and without bevacizumab (bev): a pooled analysis of the AIO KRK 0207 and RO91 trials.
J Cancer Res Clin Oncol
; 147(10): 3063-3072, 2021 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-33675399
5.
Molecular analysis of the polymorphisms of thymidylate synthase on cell-free circulating DNA in blood of patients with advanced colorectal carcinoma.
Int J Cancer
; 127(4): 881-8, 2010 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19998340
6.
Graft-versus-host disease prophylaxis with everolimus and tacrolimus is associated with a high incidence of sinusoidal obstruction syndrome and microangiopathy: results of the EVTAC trial.
Biol Blood Marrow Transplant
; 15(1): 101-8, 2009 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19135948
7.
Prediction of efficacy and side effects of chemotherapy in colorectal cancer.
Recent Results Cancer Res
; 176: 81-8, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-17607918
8.
Pharmacogenetic analysis of liver toxicity after busulfan/cyclophosphamide-based allogeneic hematopoietic stem cell transplantation.
Anticancer Res
; 27(6C): 4377-80, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-18214047
9.
Effect of Neoadjuvant Chemotherapy Followed by Surgical Resection on Survival in Patients With Limited Metastatic Gastric or Gastroesophageal Junction Cancer: The AIO-FLOT3 Trial.
JAMA Oncol
; 3(9): 1237-1244, 2017 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28448662
10.
Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer.
J Natl Cancer Inst
; 94(12): 936-42, 2002 Jun 19.
Artigo
Inglês
| MEDLINE | ID: mdl-12072547
11.
A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity.
Cancer Res
; 63(11): 2898-904, 2003 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-12782596
12.
Gene polymorphisms of epidermal growth factor receptor and its downstream effector, interleukin-8, predict oxaliplatin efficacy in patients with advanced colorectal cancer.
Clin Colorectal Cancer
; 5(2): 124-31, 2005 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-16098254
13.
Tailoring chemotherapy in advanced colorectal cancer.
Curr Opin Pharmacol
; 3(4): 378-85, 2003 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-12901946
14.
CHAMP: A Phase II Study of Panitumumab With Pemetrexed and Cisplatin Versus Pemetrexed and Cisplatin in the Treatment of Patients With Advanced-Stage Primary Nonsquamous Non-Small-Cell Lung Cancer With Particular Regard to the KRAS Status.
Clin Lung Cancer
; 16(6): 447-56, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26094080
15.
A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels.
Pharmacogenetics
; 14(5): 319-27, 2004 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15115918
16.
Cyclooxygenase-2 inhibitors in colorectal cancer.
Semin Oncol
; 30(3 Suppl 6): 10-6, 2003 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-12802790
17.
Implications of genetic testing in the management of colorectal cancer.
Am J Pharmacogenomics
; 3(2): 73-88, 2003.
Artigo
Inglês
| MEDLINE | ID: mdl-12749725
18.
Pharmacogenetic aspects in treatment of colorectal cancer--an update.
Pharmacogenomics
; 4(6): 767-77, 2003 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-14596640
19.
The -9Ala/-9Val polymorphism in the mitochondrial targeting sequence of the manganese superoxide dismutase gene (MnSOD) is associated with age among Hispanics with colorectal carcinoma.
Oncol Rep
; 9(2): 235-8, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-11836586
20.
ERCC1 gene polymorphism as a predictor for clinical outcome in advanced colorectal cancer patients treated with platinum-based chemotherapy.
Clin Adv Hematol Oncol
; 1(3): 162-6, 2003 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-16224397