Detalhe da pesquisa
1.
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Nature
; 615(7953): 678-686, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36922586
2.
A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Nature
; 598(7881): 504-509, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34616043
3.
Di-fluoro azepane HBV capsid assembly modulators.
Bioorg Med Chem Lett
; 92: 129350, 2023 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37247697
4.
Diazepinone HBV capsid assembly modulators.
Bioorg Med Chem Lett
; 72: 128823, 2022 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35644301
5.
Publisher Correction: A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Nature
; 599(7883): E2, 2021 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-34671169
6.
Oxadiazepinone HBV capsid assembly modulators.
Bioorg Med Chem Lett
; 52: 128353, 2021 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34492302
7.
Identification of a new class of HBV capsid assembly modulator.
Bioorg Med Chem Lett
; 39: 127848, 2021 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33610748
8.
Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists.
Bioorg Med Chem Lett
; 28(19): 3216-3221, 2018 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30143425
9.
Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists.
Bioorg Med Chem Lett
; 28(4): 711-719, 2018 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29366653
10.
Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor.
J Med Chem
; 67(5): 4063-4082, 2024 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38482827
11.
Design and synthesis of HIV-1 protease inhibitors for a long-acting injectable drug application.
Bioorg Med Chem Lett
; 23(1): 310-7, 2013 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23177258
12.
Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors.
J Med Chem
; 66(13): 8808-8821, 2023 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37389813
13.
From Oxetane to Thietane: Extending the Antiviral Spectrum of 2'-Spirocyclic Uridines by Substituting Oxygen with Sulfur.
ACS Med Chem Lett
; 13(12): 1879-1884, 2022 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36518706
14.
Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region.
J Med Chem
; 62(21): 9680-9690, 2019 11 14.
Artigo
Inglês
| MEDLINE | ID: mdl-31647875
15.
A small-molecule fusion inhibitor of influenza virus is orally active in mice.
Science
; 363(6431)2019 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30846569
16.
Synthesis and Evaluation of N-Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV).
J Med Chem
; 61(14): 6247-6260, 2018 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29906396
17.
2,4-Diaminoquinazolines as Dual Toll-like Receptor (TLR) 7/8 Modulators for the Treatment of Hepatitis B Virus.
J Med Chem
; 61(14): 6236-6246, 2018 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29965759
18.
Potent peptidic fusion inhibitors of influenza virus.
Science
; 358(6362): 496-502, 2017 10 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28971971
19.
Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library.
Antiviral Res
; 147: 149-158, 2017 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-29037976
20.
Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B.
J Med Chem
; 60(14): 6137-6151, 2017 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28671847