Pesquisa | Secretaria de Estado da Saúde

1.

Combinatorial Efficacy and Toxicity of an Engineered Toxin Body MT-3724 with Gemcitabine and Oxaliplatin in Relapsed or Refractory Diffuse Large B Cell Lymphoma.

Lin, Chenyu; Galal, Ahmed; Rizzieri, David; Chawla, Sant; Lee, Seung T; Georgy, Angela; Dabovic, Kristina; Strack, Thomas; McKinney, Matthew.

Cancer Invest ; : 1-10, 2023 Jan 31.

Artigo Inglês | MEDLINE | ID: mdl-36657101

2.

Safety and Efficacy of Engineered Toxin Body MT-3724 in Relapsed or Refractory B-cell Non-Hodgkin's Lymphomas and Diffuse Large B-cell Lymphoma.

Hamlin, Paul A; Musteata, Vasile; Park, Steven I; Burnett, Christine; Dabovic, Kristina; Strack, Thomas; Williams, Eric T; Anand, Banmeet S; Higgins, Jack P; Persky, Daniel O.

Cancer Res Commun ; 2(5): 307-315, 2022 05.

Artigo Inglês | MEDLINE | ID: mdl-36875713

3.

Inhaled insulin is associated with prolonged enhancement of glucose disposal in muscle and liver in the canine.

Edgerton, Dale S; Cherrington, Alan D; Neal, Doss W; Scott, Melanie; Lautz, Margaret; Brown, Nancy; Petro, Jeff; Hobbs, Charles H; Leach, Chet; Del Parigi, Angelo; Strack, Thomas R.

J Pharmacol Exp Ther ; 328(3): 970-5, 2009 Mar.

Artigo Inglês | MEDLINE | ID: mdl-19098161

4.

Glycemic exposure is affected favorably by inhaled human insulin (Exubera) as compared with subcutaneous insulin glargine (Lantus) in patients with type 2 diabetes.

Hompesch, Marcus; Kollmeier, Alexa; Rave, Klaus; Heinemann, Lutz; Mitnick, Michael; Davies, Simon; Strack, Thomas.

Diabetes Technol Ther ; 11(5): 307-13, 2009 May.

Artigo Inglês | MEDLINE | ID: mdl-19537357

5.

Phase 1 Study of High-Specific-Activity I-131 MIBG for Metastatic and/or Recurrent Pheochromocytoma or Paraganglioma.

Noto, Richard B; Pryma, Daniel A; Jensen, Jessica; Lin, Tess; Stambler, Nancy; Strack, Thomas; Wong, Vivien; Goldsmith, Stanley J.

J Clin Endocrinol Metab ; 103(1): 213-220, 2018 01 01.

Artigo Inglês | MEDLINE | ID: mdl-29099942

6.

Inhalation of human insulin (exubera) augments the efficiency of muscle glucose uptake in vivo.

Edgerton, Dale S; Cherrington, Alan D; Williams, Phillip; Neal, Doss W; Scott, Melanie; Bowen, Larry; Wilson, Warren; Hobbs, Charles H; Leach, Chet; Kuo, Mei-Chang; Strack, Thomas R.

Diabetes ; 55(12): 3604-10, 2006 Dec.

Artigo Inglês | MEDLINE | ID: mdl-17130510

7.

Phase 2 Study of ^99mTc-Trofolastat SPECT/CT to Identify and Localize Prostate Cancer in Intermediate- and High-Risk Patients Undergoing Radical Prostatectomy and Extended Pelvic LN Dissection.

Goffin, Karolien E; Joniau, Steven; Tenke, Peter; Slawin, Kevin; Klein, Eric A; Stambler, Nancy; Strack, Thomas; Babich, John; Armor, Thomas; Wong, Vivien.

J Nucl Med ; 58(9): 1408-1413, 2017 09.

Artigo Inglês | MEDLINE | ID: mdl-28302763

8.

Inhalation of insulin (Exubera) is associated with augmented disposal of portally infused glucose in dogs.

Edgerton, Dale S; Neal, Doss W; Scott, Melanie; Bowen, Larry; Wilson, Warren; Hobbs, Charles H; Leach, Chet; Sivakumaran, Shantha; Strack, Thomas R; Cherrington, Alan D.

Diabetes ; 54(4): 1164-70, 2005 Apr.

Artigo Inglês | MEDLINE | ID: mdl-15793257

9.

Synthesis and in vitro evaluation of 18F- and 19F-labeled insulin: a new radiotracer for PET-based molecular imaging studies.

Guenther, Katharina J; Yoganathan, Sabesan; Garofalo, Robert; Kawabata, Thomas; Strack, Thomas; Labiris, Renée; Dolovich, Myrna; Chirakal, Raman; Valliant, John F.

J Med Chem ; 49(4): 1466-74, 2006 Feb 23.

Artigo Inglês | MEDLINE | ID: mdl-16480283

10.

Inhalation of insulin in dogs: assessment of insulin levels and comparison to subcutaneous injection.

Cherrington, Alan D; Neal, Doss W; Edgerton, Dale S; Glass, Dana; Bowen, Larry; Hobbs, Charles H; Leach, Chet; Rosskamp, Ralf; Strack, Thomas R.

Diabetes ; 53(4): 877-81, 2004 Apr.

Artigo Inglês | MEDLINE | ID: mdl-15047601

11.

The pharmacokinetics of alternative insulin delivery systems.

Strack, Thomas.

Curr Opin Investig Drugs ; 11(4): 394-401, 2010 Apr.

Artigo Inglês | MEDLINE | ID: mdl-20336587

12.

Real-world effectiveness of new medicines should be evaluated by appropriately designed clinical trials.

Freemantle, Nick; Strack, Thomas.

J Clin Epidemiol ; 63(10): 1053-8, 2010 Oct.

Artigo Inglês | MEDLINE | ID: mdl-19880285

13.

Synthesis and characterization of rhenium and technetium-99m labeled insulin.

Sundararajan, Chitra; Besanger, Travis R; Labiris, Renee; Guenther, Katharina J; Strack, Thomas; Garafalo, Robert; Kawabata, Thomas T; Finco-Kent, Deborah; Zubieta, Jon; Babich, John W; Valliant, John F.

J Med Chem ; 53(6): 2612-21, 2010 Mar 25.

Artigo Inglês | MEDLINE | ID: mdl-20235598

14.

Assessing the impact of a new delivery method of insulin on glycemic control using a novel trial design.

Strack, Thomas; Martinez, Luc; Del Prato, Stefano; Blonde, Larry; Göke, Burkhard; Woo, Vincent; Millward, Ann; Gomis, Ramon; Canovatchel, Bill; Lawrence, David; Freemantle, Nick.

Diabetes Metab Syndr Obes ; 2: 1-10, 2009 Jan 20.

Artigo Inglês | MEDLINE | ID: mdl-21437114

15.

Imaging as a tool in drug development.

Strack, Thomas.

Drugs Today (Barc) ; 43(10): 725-36, 2007 Oct.

Artigo Inglês | MEDLINE | ID: mdl-17987225

16.

Inhaled human insulin.

Strack, Thomas R.

Drugs Today (Barc) ; 42(4): 207-21, 2006 Apr.

Artigo Inglês | MEDLINE | ID: mdl-16703118

17.

Will availability of inhaled human insulin (Exubera) improve management of type 2 diabetes? The design of the Real World trial.

Freemantle, Nick; Strack, Thomas R.

Trials ; 7: 25, 2006 Aug 10.

Artigo Inglês | MEDLINE | ID: mdl-16901335

18.

Inhalation of human insulin is associated with improved insulin action compared with subcutaneous injection and endogenous secretion in dogs.

Edgerton, Dale S; Stettler, Kathryn M; Neal, Doss W; Scott, Melanie; Bowen, Larry; Wilson, Warren; Hobbs, Charles H; Leach, Chet; Strack, Thomas R; Cherrington, Alan D.

J Pharmacol Exp Ther ; 319(3): 1258-64, 2006 Dec.

Artigo Inglês | MEDLINE | ID: mdl-16963622

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