Detalhe da pesquisa
1.
High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-ß-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors.
Molecules
; 24(7)2019 Apr 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30987252
2.
Probing the ß-pocket of the active site of human liver glycogen phosphorylase with 3-(C-ß-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorg Chem
; 77: 485-493, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29454281
3.
van der Waals interactions govern C-ß-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
J Struct Biol
; 199(1): 57-67, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28483603
4.
Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography.
J Med Chem
; 62(13): 6116-6136, 2019 07 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31251604
5.
A multidisciplinary study of 3-(ß-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors.
Eur J Med Chem
; 147: 266-278, 2018 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-29453094
6.
Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase.
Curr Drug Discov Technol
; 15(1): 41-53, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-28625148
7.
Oxidation of human serum albumin exhibits inter-individual variability after an ultra-marathon mountain race.
Exp Ther Med
; 13(5): 2382-2390, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-28565852
8.
Phytogenic Polyphenols as Glycogen Phosphorylase Inhibitors: The Potential of Triterpenes and Flavonoids for Glycaemic Control in Type 2 Diabetes.
Curr Med Chem
; 24(4): 384-403, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-27855623
9.
Nanomolar Inhibitors of Glycogen Phosphorylase Based on ß-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study.
J Med Chem
; 60(22): 9251-9262, 2017 11 22.
Artigo
Inglês
| MEDLINE | ID: mdl-28925695
10.
The ammonium sulfate inhibition of human angiogenin.
FEBS Lett
; 590(17): 3005-18, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27483019
11.
Synthetic, enzyme kinetic, and protein crystallographic studies of C-ß-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
Eur J Med Chem
; 123: 737-745, 2016 Nov 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27522507
12.
Natural flavonoids as antidiabetic agents. The binding of gallic and ellagic acids to glycogen phosphorylase b.
FEBS Lett
; 589(15): 1787-94, 2015 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-25980608
13.
Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N´-(ß-D-glucopyranosyl) urea inhibitors.
Curr Top Med Chem
; 15(23): 2373-89, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26088352
14.
Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase.
Food Chem Toxicol
; 67: 35-43, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24556570