Detalhe da pesquisa
1.
Engineering of weak helper interactions for high-efficiency FRET probes.
Nat Methods
; 10(10): 1021-7, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23995386
2.
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases.
Nature
; 456(7218): 107-11, 2008 Nov 06.
Artigo
Inglês
| MEDLINE | ID: mdl-18987743
3.
BriX: a database of protein building blocks for structural analysis, modeling and design.
Nucleic Acids Res
; 39(Database issue): D435-42, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20972210
4.
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res
; 39(2): 729-43, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20846960
5.
A graphical interface for the FoldX forcefield.
Bioinformatics
; 27(12): 1711-2, 2011 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21505037
6.
PepX: a structural database of non-redundant protein-peptide complexes.
Nucleic Acids Res
; 38(Database issue): D545-51, 2010 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19880386
7.
Using protein design algorithms to understand the molecular basis of disease caused by protein-DNA interactions: the Pax6 example.
Nucleic Acids Res
; 38(21): 7422-31, 2010 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-20685816
8.
Directed evolution of prenylated FMN-dependent Fdc supports efficient in vivo isobutene production.
Nat Commun
; 12(1): 5300, 2021 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34489427
9.
Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences.
Nucleic Acids Res
; 36(7): 2163-73, 2008 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-18276641
10.
How protein stability and new functions trade off.
PLoS Comput Biol
; 4(2): e1000002, 2008 Feb 29.
Artigo
Inglês
| MEDLINE | ID: mdl-18463696
11.
Reconstruction of protein backbones from the BriX collection of canonical protein fragments.
PLoS Comput Biol
; 4(5): e1000083, 2008 May 23.
Artigo
Inglês
| MEDLINE | ID: mdl-18483555
12.
Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm.
PLoS Comput Biol
; 4(4): e1000052, 2008 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-18389064
13.
The stability effects of protein mutations appear to be universally distributed.
J Mol Biol
; 369(5): 1318-32, 2007 Jun 22.
Artigo
Inglês
| MEDLINE | ID: mdl-17482644
14.
Quantifying information transfer by protein domains: analysis of the Fyn SH2 domain structure.
BMC Struct Biol
; 8: 43, 2008 Oct 08.
Artigo
Inglês
| MEDLINE | ID: mdl-18842137
15.
Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets.
J Mol Biol
; 355(3): 443-58, 2006 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-16310802
16.
Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes.
Nat Biotechnol
; 21(1): 71-6, 2003 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-12483221
17.
The FoldX web server: an online force field.
Nucleic Acids Res
; 33(Web Server issue): W382-8, 2005 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15980494
18.
SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs.
Nucleic Acids Res
; 33(Database issue): D527-32, 2005 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15608254
19.
Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.
Structure
; 13(5): 755-68, 2005 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15893666
20.
Design of miniproteins by the transfer of active sites onto small-size scaffolds.
Methods Mol Biol
; 340: 113-49, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-16957335