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1.
Can J Urol ; 20(4): 6840-3, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23930609

RESUMO

INTRODUCTION: To evaluate the use of ultrasound (US) at the time of percutaneous suprapubic catheter (SPC) placement. US has been recommended as a way to minimize complications, such as bowel injury, during percutaneous SPC placement, yet there is limited data supporting this recommendation. MATERIALS AND METHODS: A retrospective chart review was performed on patients undergoing percutaneous SPC placement from 2002 to 2011. The method of percutaneous SPC placement (cystoscopic and/or ultrasound guidance, blind) was recorded and patients were subdivided into groups based on the use of US. The need to modify the approach based on US findings and complications such as bleeding or bowel injury were noted and compared between groups. RESULTS: A total of 307 percutaneous SPCs were placed: cystoscopy alone was used in 190 (62%) patients, cystoscopy + US in 86 (28%) patients, US alone in 6 (2%) patients, and 25 (8%) patients had the SPC placed blindly. Previous lower abdominal surgery was noted in 41/92 (45%) of patients with and 32/215 (15%) of patients without US usage. US identified intervening loops of bowel in 5/92 cases (5%), all of whom had a history of lower abdominal surgery. The approach was modified in 2/5 and abandoned in 3/5 based on US findings. Postoperative bleeding occurred in 1/215 (0.5%) of patients with and 1/92 (1%) of patients without US usage. No bowel injuries occurred. CONCLUSIONS: While US may not be needed in most patients, particularly when cystoscopy is used, it may help to avoid bowel injury in patients with a history of lower abdominal surgery.


Assuntos
Abdome/diagnóstico por imagem , Cateterismo/métodos , Ultrassonografia/métodos , Cateteres Urinários , Adulto , Idoso , Cistoscopia , Feminino , Trato Gastrointestinal/lesões , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Obstrução do Colo da Bexiga Urinária/terapia , Bexiga Urinaria Neurogênica/terapia
2.
Ultrasound Q ; 36(1): 1-5, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31107426

RESUMO

Structured reporting of ultrasound examinations can add value throughout the imaging chain. Reports may be created in a more efficient manner, with increased accuracy and clarity. Communication with referring providers and patients may be improved. Patient care can be enhanced through improved adherence with guidelines and local best practices. Radiology departments may benefit from improved billing and quality reporting. Consistent discrete data can enable research and collaborations between institutions. This article will review the multifaceted impact of structuring ultrasound reports.


Assuntos
Documentação/normas , Sistemas de Informação em Radiologia/normas , Ultrassonografia , Humanos , Melhoria de Qualidade
3.
Ultrasound Q ; 35(4): 316-324, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30724870

RESUMO

Portal venous system evaluation is required in many clinical circumstances, as substantial morbidity and mortality can be associated with a spectrum of portal vein abnormalities. Portal venous system pathologies can be congenital or acquired, and the knowledge of their imaging appearances will allow for a confident diagnosis and appropriate treatment options. In addition, a firm understanding of anatomical variants is important for planning surgical procedures and percutaneous interventions of the liver. This article will review various imaging appearances of portal venous systems abnormalities.


Assuntos
Veia Porta/diagnóstico por imagem , Ultrassonografia/métodos , Malformações Vasculares/diagnóstico , Humanos
4.
Ultrasound Q ; 35(4): 346-354, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30807547

RESUMO

Magnetic resonance-guided focused ultrasound (MRgFUS) utilizes high-intensity focused ultrasound to noninvasively, thermally ablate lesions within the body while sparing the intervening tissues. Magnetic resonance imaging provides treatment planning and guidance, and real-time magnetic resonance thermometry provides continuous monitoring during therapy. Magnetic resonance-guided focused ultrasound is ideally suited for the treatment of extra-abdominal desmoid fibromatosis due to its noninvasiveness, lack of ionizing radiation, low morbidity, and good safety profile. Conventional treatments for these benign tumors, including surgery, radiation, and chemotherapy, can carry significant morbidity. Magnetic resonance-guided focused ultrasound provides a safe and effective alternative treatment in this often-young and otherwise healthy patient population. While there is considerable experience with MRgFUS for treatment of uterine fibroids, painful bone lesions, and essential tremor, there are few reports in the literature of its use for treatment of benign or malignant soft tissue tumors. This article reviews the principles and biologic effects of high-intensity focused ultrasound, provides an overview of the MRgFUS treatment system and use of magnetic resonance thermometry, discusses the use of MRgFUS for the treatment of extra-abdominal desmoid tumors, and provides several case examples.


Assuntos
Fibromatose Agressiva/terapia , Ablação por Ultrassom Focalizado de Alta Intensidade/métodos , Imageamento por Ressonância Magnética/métodos , Terapia Assistida por Computador/métodos , Fibromatose Agressiva/diagnóstico , Humanos
5.
J Urol ; 179(3): 862-7; discussion 867, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18221955

RESUMO

PURPOSE: We determined whether multidetector computerized tomography urography is sensitive and specific for detecting urinary tract neoplasms when used as the primary imaging modality for evaluating patients with hematuria. MATERIALS AND METHODS: A retrospective review was performed of the radiological, urological and pathological records of 468 patients without a history of urinary neoplasms who presented with hematuria. All patients underwent multidetector computerized tomography urography and complete urological evaluation, including cystoscopy. Laboratory urinalysis and cytology were done in 350 and 318 of the 468 patients, respectively. Multivariate logistic regression analysis was performed using the variables multidetector computerized tomography urography diagnosis, worst urine cytology, number of red blood cells per high power field, gross hematuria, age and gender to predict urinary tract neoplasm. RESULTS: A total of 50 urinary neoplasms were diagnosed in 468 patients. Multidetector computerized tomography urography detected 32 of 50 neoplasms for a sensitivity of 64%, specificity of 98%, positive predictive value of 76% and negative predictive value of 96%. There were 10 false-positive and 18 false-negative multidetector computerized tomography urography studies. Multivariate logistic regression showed that abnormal multidetector computerized tomography urography findings, ie neoplasm (p <0.0001), and suspicious or positive urine cytology (p = 0.0009) were significant. Patients with an abnormal multidetector computerized tomography urography diagnosis and suspicious or positive urine cytology had 44 and 47 times greater odds, respectively, of having urinary neoplasms compared to the odds in those with normal examinations. CONCLUSIONS: Multidetector computerized tomography urography is relatively sensitive and highly specific for detecting urinary neoplasms. It may serve as the primary imaging modality to evaluate patients with hematuria. Multidetector computerized tomography urography does not eliminate the role of cystoscopy in the evaluation of hematuria.


Assuntos
Hematúria/etiologia , Tomografia Computadorizada por Raios X , Urografia , Neoplasias Urológicas/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Sensibilidade e Especificidade , Neoplasias Urológicas/complicações
6.
WMJ ; 106(1): 34-6, 2007 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-17393756

RESUMO

While the liver is a common site of metastasis, tumor metastases are not a common cause of portal hypertension. We report a case of a patient with symptomatic portal hypertension due to diffuse metastatic prostate carcinoma infiltration of liver parenchyma that was not appreciated with routine imaging.


Assuntos
Hipertensão Portal/etiologia , Neoplasias da Próstata/complicações , Biópsia , Humanos , Hipertensão Portal/diagnóstico por imagem , Hipertensão Portal/patologia , Masculino , Pessoa de Meia-Idade , Metástase Neoplásica , Neoplasias da Próstata/diagnóstico por imagem , Neoplasias da Próstata/patologia , Tomografia Computadorizada por Raios X
7.
J Am Coll Radiol ; 14(5S): S154-S159, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28473071

RESUMO

Most men with hematospermia or hemospermia (HS) are young (<40 years of age), presenting with transient or episodic HS without other signs or symptoms of disease. The condition is self-limiting in most cases and idiopathic in nature. When a cause can be identified, infections of the urogenital tract are the most common. Imaging does not play a role in this patient population. In older men (>40 years of age), clinical screening for prostate cancer is advised. Furthermore, when HS is persistent or has symptoms, causes include obstruction or stricture at the level of the verumontanum, calcifications or calculi in the prostate, ejaculatory ducts or seminal vesicles, and cysts arising within these structures. Noninvasive imaging, predominantly transrectal ultrasound (TRUS) and MRI, can be used in men of any age with persistent or refractory HS, or other associated symptoms or signs. TRUS is considered as the first-line imaging with MRI used when TRUS is inconclusive or negative. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.


Assuntos
Hemospermia/diagnóstico por imagem , Fatores Etários , Hemospermia/etiologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Doenças Prostáticas/complicações , Neoplasias da Próstata/complicações , Radiologia , Sociedades Médicas , Tomografia Computadorizada por Raios X , Ultrassonografia/métodos , Estados Unidos , Infecções Urinárias/complicações
8.
J Am Coll Radiol ; 13(10): 1203-1209, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27526969

RESUMO

Testicular cancer represents only 1% of all malignancies occurring in men. However, it is the most frequent malignancy in men between the ages of 20 and 34 years, accounting for 10% to 14% of cancer incidence in that age group. In most instances, the diagnosis of testicular tumors is established with a carefully performed physical examination and scrotal ultrasonography. Tumor markers are useful for determining the presence of residual disease. Cross-sectional imaging studies (CT, MRI) are useful in determining the location of metastases. Chest radiography and CT are used to assess pulmonary disease. Fluorine-18-2-fluoro-2-deoxy-d-glucose (FDG) PET scans have slightly higher sensitivity than CT, but their role in staging testicular cancer has not been determined in a large study. FDG PET may play a role in the follow-up of higher stage seminoma after chemotherapy. Bone scans are useful in the absence of FDG PET scans and should be used when bone metastases are suspected. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (the RAND/UCLA Appropriateness Method and the Grading of Recommendations Assessment, Development, and Evaluation) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances in which evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.


Assuntos
Diagnóstico por Imagem/normas , Neoplasias Testiculares/diagnóstico por imagem , Neoplasias Testiculares/patologia , Adulto , Biomarcadores Tumorais/análise , Medicina Baseada em Evidências , Humanos , Incidência , Masculino , Estadiamento de Neoplasias , Exame Físico , Sensibilidade e Especificidade , Neoplasias Testiculares/epidemiologia , Estados Unidos/epidemiologia
9.
Ultrasound Q ; 21(3): 175-85, 2005 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-16096614

RESUMO

Infected pelvic fluid collections are relatively common particularly after abdominal or pelvic surgery or in patients suffering from benign intestinal disease such as diverticulitis, appendicitis, or Crohn's disease. Historically the treatment of pelvic abscess has been either laparotomy with lavage or blind surgical incision and drainage through the rectal or vaginal wall. More recently, computed tomography and ultrasound-guided percutaneous drainage has become the procedure of choice, when feasible, for the treatment of pelvic abscess. However, many deep pelvic collections are not amenable to percutaneous technique. Transrectal or transvaginal ultrasound-guided abscess drainage is a safe and effective method used in the treatment of deep pelvic abscesses. The purpose of this article is to review the techniques, patient selection, pre- and post-procedural care, and monitoring aspects of transrectal or transvaginal ultrasound-guided drainage.


Assuntos
Abscesso/diagnóstico por imagem , Abscesso/terapia , Pelve/diagnóstico por imagem , Complicações Pós-Operatórias/diagnóstico por imagem , Complicações Pós-Operatórias/terapia , Ultrassonografia de Intervenção , Antibioticoprofilaxia , Drenagem , Feminino , Humanos , Masculino , Monitorização Fisiológica , Reto , Vagina
10.
Inflamm Bowel Dis ; 9(1): 25-7, 2003 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-12656134

RESUMO

Small bowel calcification is a rare finding, often associated with chronic infection or small intestinal neoplasms. The authors report a patient who developed dystrophic ileal calcification in the setting of medically refractory Crohn's disease. The patient had longstanding, obstructive ileal Crohn's disease, treated with corticosteroids for a 10-year period. Diffuse terminal ileal calcification was evident on radiographic studies, including plain films as well as abdominal CT scan. The patient underwent successful resection of the diseased segment of small bowel and has done well over the ensuing 3-year period. Dystrophic calcification is a rare complication of long-standing chronic inflammation in Crohn's disease that may occur in the absence of adenocarcinoma or chronic infection.


Assuntos
Calcinose/diagnóstico , Calcinose/etiologia , Doença de Crohn/complicações , Doença de Crohn/diagnóstico , Doenças do Íleo/diagnóstico , Doenças do Íleo/etiologia , Calcinose/cirurgia , Doença de Crohn/cirurgia , Humanos , Doenças do Íleo/cirurgia , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios X
11.
Surgery ; 136(4): 854-60, 2004 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-15467672

RESUMO

BACKGROUND: The purpose of this study was to determine the accuracy of barium radiography compared with intraoperative evaluation with passage of a balloon catheter for assessment of stricturing Crohn's disease (CD). METHODS: After institutional review board approval, we retrospectively reviewed a tertiary inflammatory bowel disease center's consecutive records of surgical patients between 1998 and 2003 with small intestinal CD to compare the number of strictures found at surgery with those identified preoperatively by barium imaging. Age, gender, prior surgical procedures, and steroid usage were recorded. By decision of the surgeons, all patients were treated with an identical approach that utilized intraluminal sizing with passage of a balloon-tipped catheter. RESULTS: In 118 patients, 230 strictures were identified by barium examination; 365 strictures were identified using the balloon catheter technique. Barium examination overestimated or underestimated the number of strictures in 43 of 118 patients (36%). Overall, barium radiography was least accurate in patients with strictures amenable to strictureplasty. Prior surgery and multiple strictures identified preoperatively by barium studies were found to decrease the accuracy of the barium examination, but the decrease did not reach statistical significance. After successful surgery for stricturing small intestinal CD, more than 90% of patients can successfully be weaned from their steroids within 3 months. Failure to be able to wean from steroids may suggest a missed stricture. CONCLUSIONS: Our data suggest that careful exploration and intraoperative, intraluminal testing of intestinal patency identify additional strictures compared with barium radiographs in a significant number of patients with CD undergoing small bowel surgical intervention.


Assuntos
Doença de Crohn/diagnóstico por imagem , Doença de Crohn/cirurgia , Adolescente , Adulto , Idoso , Sulfato de Bário , Pesos e Medidas Corporais , Cateterismo/instrumentação , Constrição Patológica , Meios de Contraste , Procedimentos Cirúrgicos do Sistema Digestório/métodos , Feminino , Humanos , Intestino Delgado/diagnóstico por imagem , Intestino Delgado/patologia , Masculino , Pessoa de Meia-Idade , Radiografia , Estudos Retrospectivos
13.
Arch Pathol Lab Med ; 126(12): 1530-3, 2002 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-12456217

RESUMO

Adrenal tumors often present with clinical features that are specific and unique to their endocrine metabolism. When these features are in conflict with the pathologic appearance of the tumor, there can be great consternation for both the pathologist and the surgeon. In the case reported herein, an adrenalectomy was performed for clinical features of pheochromocytoma that on gross and histologic examination had the pathologic features of an adrenal cortical adenoma. Electron microscopy subsequently revealed that the tumor cells contained adrenalin-type granules, explaining the clinical outcome. It is crucial for both the surgeon and the surgical pathologist to be aware of this possibility when the clinical and pathologic features of an adrenal tumor are not congruent.


Assuntos
Neoplasias do Córtex Suprarrenal/patologia , Neoplasias das Glândulas Suprarrenais/patologia , Adenoma Adrenocortical/patologia , Epinefrina/metabolismo , Feocromocitoma/patologia , Vesículas Secretórias/patologia , Neoplasias do Córtex Suprarrenal/ultraestrutura , Neoplasias das Glândulas Suprarrenais/ultraestrutura , Adenoma Adrenocortical/ultraestrutura , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , Feocromocitoma/ultraestrutura , Vesículas Secretórias/ultraestrutura
14.
Ultrasound Q ; 18(4): 255-73, 2002 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-12973097

RESUMO

Sonography is the imaging modality of choice in detecting and characterizing pathologic conditions affecting the extratesticular space. Although most abnormalities are benign, many may simulate or represent malignant processes. Accurate diagnosis is therefore essential and must be based not only on the sonographic findings but also on accurate clinical history and physical examination findings. This article reviews the anatomy, embryologic development, and pathologic conditions affecting the extratesticular space.

15.
J Am Coll Radiol ; 10(6): 402-9, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23632132

RESUMO

A fundamental consideration in the workup of a jaundiced patient is the pretest probability of mechanical obstruction. Ultrasound is the first-line modality to exclude biliary tract obstruction. When mechanical obstruction is present, additional imaging with CT or MRI can clarify etiology, define level of obstruction, stage disease, and guide intervention. When mechanical obstruction is absent, additional imaging can evaluate liver parenchyma for fat and iron deposition and help direct biopsy in cases where underlying parenchymal disease or mass is found. Imaging techniques are reviewed for the following clinical scenarios: (1) the patient with painful jaundice, (2) the patient with painless jaundice, and (3) the patient with a nonmechanical cause for jaundice. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 2 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.


Assuntos
Colestase/diagnóstico , Colestase/etiologia , Diagnóstico por Imagem/normas , Icterícia/complicações , Icterícia/diagnóstico , Guias de Prática Clínica como Assunto , Radiologia/normas , Humanos , Estados Unidos
16.
J Am Coll Radiol ; 9(11): 775-81, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23122343

RESUMO

Because virtually all patients with colonic cancer will undergo some form of surgical therapy, the role of preoperative imaging is directed at determining the presence or absence of synchronous carcinomas or adenomas and local or distant metastases. In contrast, preoperative staging for rectal carcinoma has significant therapeutic implications and will direct the use of radiation therapy, surgical excision, or chemotherapy. CT of the chest, abdomen, and pelvis is recommended for the initial evaluation for the preoperative assessment of patients with colorectal carcinoma. Although the overall accuracy of CT varies directly with the stage of colorectal carcinoma, CT can accurately assess the presence of metastatic disease. MRI using endorectal coils can accurately assess the depth of bowel wall penetration of rectal carcinomas. Phased-array coils provide additional information about lymph node involvement. Adding diffusion-weighted imaging to conventional MRI yields better diagnostic accuracy than conventional MRI alone. Transrectal ultrasound can distinguish layers within the rectal wall and provides accurate assessment of the depth of tumor penetration and perirectal spread, and PET and PET/CT have been shown to alter therapy in almost one-third of patients with advanced primary rectal cancer. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 2 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances in which evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.


Assuntos
Neoplasias Colorretais/diagnóstico , Neoplasias Colorretais/patologia , Diagnóstico por Imagem/normas , Guias de Prática Clínica como Assunto , Cuidados Pré-Operatórios/normas , Neoplasias Colorretais/terapia , Humanos , Estadiamento de Neoplasias , Radiologia/normas
17.
J Am Coll Radiol ; 8(11): 749-55, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22051456

RESUMO

The diagnostic imaging of patients presenting with right lower quadrant pain and suspected appendicitis may be organized according to age and gender and to the presence or absence of "classic" signs and symptoms of acute appendicitis. Among adult patients presenting with clinical signs of acute appendicitis, the sensitivity and specificity of CT are greater than those of ultrasound, with improved performance when CT is performed with intravenous contrast. The use of rectal contrast has been associated with decreased time in the emergency department. Computed tomography has also been shown to reduce cost and negative appendectomy rates. Both CT and ultrasound are also effective in the identification of causes of right lower quadrant pain unrelated to appendicitis. Among pediatric patients, the sensitivity and specificity of graded-compression ultrasound can approach those of CT, without the use of ionizing radiation. Performing MRI after inconclusive ultrasound in pregnant patients has been associated with sensitivity and specificity of 80% to 86% and 97% to 99%, respectively. The ACR Appropriateness Criteria(®) are evidence-based guidelines for specific clinical conditions that are reviewed every 2 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances in which evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.


Assuntos
Apendicite/diagnóstico , Diagnóstico por Imagem/normas , Guias de Prática Clínica como Assunto/normas , Efeitos da Radiação , Abdome Agudo/diagnóstico , Dor Abdominal/diagnóstico , Diagnóstico Diferencial , Diagnóstico por Imagem/efeitos adversos , Feminino , Humanos , Imageamento por Ressonância Magnética/efeitos adversos , Imageamento por Ressonância Magnética/normas , Masculino , Gravidez , Proteção Radiológica , Medição de Risco , Sensibilidade e Especificidade , Sociedades Médicas/normas , Tomografia Computadorizada por Raios X/efeitos adversos , Tomografia Computadorizada por Raios X/métodos , Ultrassonografia Doppler/efeitos adversos , Ultrassonografia Doppler/normas
18.
J Palliat Med ; 13(9): 1125-9, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20836637

RESUMO

PURPOSE: Men with metastatic castrate-resistant prostate cancer (mCRPC) have shown increased survival since the introduction of docetaxel-based chemotherapy in 2004. While bone metastases are common in prostate cancer, cranial dural metastases (DM) are not. We hypothesize that longer survival in patients with mCRPC may increase the incidence of uncommon metastatic sites, including the cranial dura. We describe 10 cases of DM in men with mCRPC and review the relevant literature. MATERIALS AND METHODS: We conducted a retrospective chart review of 10 subjects with mCRPC, diagnosed ante-mortem with DM at our institution between August 1, 2003 and June 1, 2008. Variables analyzed included prognostic factors at prostate cancer diagnosis, number of therapies prior to DM, treatments administered for DM with response achieved, and survival following diagnosis of DM. RESULTS: Median age at prostate cancer diagnosis was 59 years (range, 52-80), with a median Gleason's score of 9 (range, 8-10) and prostate-specific antigen (PSA) of 37 ng/dL (range, 4.9-118). Fifty percent had metastatic disease at initial diagnosis. A median of 5 therapies (range, 1-13) were administered prior to diagnosis of DM, including a median of 1 course of chemotherapy (range, 1-3). Cranial neuropathies were the most common presenting symptoms of DM, and 8 of 10 patients received treatment for their DM, most often radiotherapy. Median survival for this group was 6.17 months (range, < 1-15). CONCLUSIONS: Treatment advances in mCRPC may lead to an increased incidence of previously rare metastatic sites. CNS symptoms in men with mCRPC should prompt evaluation for DM.


Assuntos
Neoplasias da Próstata/patologia , Idoso , Idoso de 80 Anos ou mais , Autopsia , Biomarcadores Tumorais/análise , Meios de Contraste , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Antígeno Prostático Específico/análise , Neoplasias da Próstata/terapia , Estudos Retrospectivos , Análise de Sobrevida , Resultado do Tratamento
19.
J Am Coll Radiol ; 7(2): 94-102, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20142082

RESUMO

In the past decade, new therapeutic agents have been developed that permit gastroenterologists to treat virtually all forms of Crohn's disease. The success of these treatments depends on an accurate diagnosis of the nature and extent of disease. Fortunately, radiologists now possess a powerful arsenal of imaging techniques to guide the choice of therapy. This article discusses the usefulness of both traditional and newer imaging techniques in the management of Crohn's disease and its various clinical presentations.


Assuntos
Doença de Crohn/diagnóstico , Doença de Crohn/terapia , Diagnóstico por Imagem/normas , Guias de Prática Clínica como Assunto , Humanos
20.
J Am Coll Radiol ; 7(9): 670-8, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20816627

RESUMO

Colorectal cancer remains one of the most common causes of cancer death in this country. This malignancy is ideally suited for screening because the detection and removal of the precursor adenomatous polyp can prevent most colorectal cancers from ever forming. The choice of a test for screening involves consideration of various individual parameters, including patient age and the presence of risk factors for the development of colorectal cancer. Computed tomographic colonography (CTC) has emerged as the leading imaging technique for colorectal cancer screening in average-risk individuals on the basis of the evidence presented in this paper. The double-contrast barium enema is an alternative imaging test that is appropriate particularly when CTC is not available. In 2008, the American Cancer Society guideline for colorectal cancer screening was revised jointly with the US Multi-Society Task Force on Colorectal Cancer and the ACR to include CTC every 5 years as an option for average-risk individuals. Computed tomographic colonography is also the preferred test for colon evaluation after an incomplete colonoscopy. Imaging tests including CTC and the double-contrast barium enema are usually not indicated for colorectal cancer screening in high-risk patients with polyposis syndromes or inflammatory bowel disease. This paper presents the new colorectal cancer imaging test ratings and is the result of evidence-based consensus by the ACR Appropriateness Criteria Expert Panel on Gastrointestinal Imaging.


Assuntos
Neoplasias Colorretais/prevenção & controle , Programas de Rastreamento/normas , Radiologia/estatística & dados numéricos , Adenoma/complicações , Biópsia , Colite Ulcerativa/diagnóstico por imagem , Colonografia Tomográfica Computadorizada/métodos , Colonoscopia/estatística & dados numéricos , Neoplasias Colorretais/diagnóstico por imagem , Neoplasias Colorretais/epidemiologia , Neoplasias Colorretais/mortalidade , Doença de Crohn/diagnóstico por imagem , Humanos , Programas de Rastreamento/estatística & dados numéricos , Radiologia/normas , Medição de Risco , Taxa de Sobrevida , Tomografia Computadorizada por Raios X/métodos , Estados Unidos/epidemiologia
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