Detalhe da pesquisa
1.
Targeting Astrocyte Signaling Alleviates Cerebrovascular and Synaptic Function Deficits in a Diet-Based Mouse Model of Small Cerebral Vessel Disease.
J Neurosci
; 43(10): 1797-1813, 2023 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36746627
2.
Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort.
Alzheimers Dement
; 20(2): 1374-1386, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38011580
3.
Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes.
J Neuroinflammation
; 20(1): 199, 2023 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37658433
4.
Associations of potential ADRD plasma biomarkers in cognitively normal volunteers.
Alzheimers Dement
; 19(8): 3593-3601, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36840666
5.
Examining the association between blood-based biomarkers and human post mortem neuropathology in the University of Kentucky Alzheimer's Disease Research Center autopsy cohort.
Alzheimers Dement
; 19(1): 67-78, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35266629
6.
Plasma amyloid beta, neurofilament light chain, and total tau in the Systolic Blood Pressure Intervention Trial (SPRINT).
Alzheimers Dement
; 18(8): 1472-1483, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34786815
7.
Delayed diapedesis of CD8 T cells contributes to long-term pathology after ischemic stroke in male mice.
Brain Behav Immun
; 95: 502-513, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33964435
8.
Water exchange rate across the blood-brain barrier is associated with CSF amyloid-ß 42 in healthy older adults.
Alzheimers Dement
; 17(12): 2020-2029, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33949773
9.
Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition.
J Neuroinflammation
; 17(1): 238, 2020 Aug 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32795308
10.
Time course of neuropathological events in hyperhomocysteinemic amyloid depositing mice reveals early neuroinflammatory changes that precede amyloid changes and cerebrovascular events.
J Neuroinflammation
; 16(1): 284, 2019 Dec 30.
Artigo
Inglês
| MEDLINE | ID: mdl-31888650
11.
Reduced Efficacy of Anti-Aß Immunotherapy in a Mouse Model of Amyloid Deposition and Vascular Cognitive Impairment Comorbidity.
J Neurosci
; 36(38): 9896-907, 2016 09 21.
Artigo
Inglês
| MEDLINE | ID: mdl-27656027
12.
Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-ß using BV2 microglial cells and APP/PS1 transgenic mice.
J Neuroinflammation
; 12: 41, 2015 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-25885682
13.
Intracranial injection of Gammagard, a human IVIg, modulates the inflammatory response of the brain and lowers Aß in APP/PS1 mice along a different time course than anti-Aß antibodies.
J Neurosci
; 33(23): 9684-92, 2013 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-23739965
14.
Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice.
J Neuroinflammation
; 11: 127, 2014 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-25062954
15.
Plasma TDP-43 levels are associated with neuroimaging measures of brain structure in limbic regions.
Alzheimers Dement (Amst)
; 15(2): e12437, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37266411
16.
Apolipoprotein E ε4/4 genotype limits response to dietary induction of hyperhomocysteinemia and resulting inflammatory signaling.
J Cereb Blood Flow Metab
; 42(5): 771-787, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35023380
17.
Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue.
Alzheimers Dement (N Y)
; 8(1): e12368, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36514441
18.
Hierarchical Clustering Analyses of Plasma Proteins in Subjects With Cardiovascular Risk Factors Identify Informative Subsets Based on Differential Levels of Angiogenic and Inflammatory Biomarkers.
Front Neurosci
; 14: 84, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32116527
19.
Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia.
Geroscience
; 41(5): 671-679, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31104189
20.
Hyperhomocysteinemia-Induced Gene Expression Changes in the Cell Types of the Brain.
ASN Neuro
; 9(6): 1759091417742296, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-29198136