Detalhe da pesquisa
1.
Tyrosine hydroxylase conditional KO mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways.
J Biol Chem
; 296: 100544, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33737022
2.
Perturbation of monoamine metabolism and enhanced fear responses in mice defective in the regeneration of tetrahydrobiopterin.
J Neurochem
; 161(2): 129-145, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35233765
3.
Priapism caused by partial deficiency of tetrahydrobiopterin through hypofunction of the sympathetic neurons in sepiapterin reductase gene-disrupted mice.
J Inherit Metab Dis
; 45(3): 621-634, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35192730
4.
Quinonoid dihydropteridine reductase, a tetrahydrobiopterin-recycling enzyme, contributes to 5-hydroxytryptamine-associated platelet aggregation in mice.
J Pharmacol Sci
; 150(3): 173-179, 2022 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-36184122
5.
Partial biopterin deficiency disturbs postnatal development of the dopaminergic system in the brain.
J Biol Chem
; 286(2): 1445-52, 2011 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-21062748
6.
Compensatory regulation of dopamine after ablation of the tyrosine hydroxylase gene in the nigrostriatal projection.
J Biol Chem
; 286(50): 43549-58, 2011 Dec 16.
Artigo
Inglês
| MEDLINE | ID: mdl-22027820
7.
Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia.
Proc Natl Acad Sci U S A
; 105(34): 12551-6, 2008 Aug 26.
Artigo
Inglês
| MEDLINE | ID: mdl-18713855
8.
Salivary neopterin and related pterins: their comparison to those in plasma and changes in individuals.
J Biochem
; 170(4): 559-567, 2021 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34181024
9.
Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons.
J Neurosci
; 29(50): 15923-32, 2009 Dec 16.
Artigo
Inglês
| MEDLINE | ID: mdl-20016108
10.
Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: regulation of dopaminergic neural transmission by tyrosine hydroxylase protein at nerve terminals.
J Pharmacol Sci
; 114(1): 17-24, 2010.
Artigo
Inglês
| MEDLINE | ID: mdl-20716859
11.
2,4-Diamino-6-hydroxypyrimidine (DAHP) suppresses cytokine-induced VCAM-1 expression on the cell surface of human umbilical vein endothelial cells in a BH(4)-independent manner.
Biochim Biophys Acta
; 1780(7-8): 960-5, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-18423409
12.
A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice--as a mouse model for Parkinson's disease.
Biochem Biophys Res Commun
; 367(4): 787-92, 2008 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-18201550
13.
Increased expression of tyrosine hydroxylase and anomalous neurites in catecholaminergic neurons of ATF-2 null mice.
J Neurosci Res
; 86(3): 544-52, 2008 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17896792
14.
Metabolism of tetrahydrobiopterin: its relevance in monoaminergic neurons and neurological disorders.
Chem Rec
; 8(6): 378-85, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-19107867
15.
Sepiapterin reductase gene-disrupted mice suffer from hypertension with fluctuation and bradycardia.
Physiol Rep
; 5(6)2017 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-28320892
16.
cAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells.
Life Sci
; 70(18): 2187-98, 2002 Mar 22.
Artigo
Inglês
| MEDLINE | ID: mdl-12002810
17.
Disturbed biopterin and folate metabolism in the Qdpr-deficient mouse.
FEBS Lett
; 588(21): 3924-31, 2014 Nov 03.
Artigo
Inglês
| MEDLINE | ID: mdl-25240194
18.
Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia.
Mol Brain
; 7: 21, 2014 Mar 29.
Artigo
Inglês
| MEDLINE | ID: mdl-24678719
19.
GTP cyclohydrolase regulation: implications for brain development and function.
Adv Pharmacol
; 68: 23-35, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24054139
20.
Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy.
Neuroreport
; 23(1): 30-4, 2012 Jan 04.
Artigo
Inglês
| MEDLINE | ID: mdl-22107842