1.
Angew Chem Int Ed Engl
; 62(22): e202303229, 2023 May 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36952314
RESUMO
Naphthospironone A, a polyhydroxy cagelike bioactive natural product, was synthesised for the first time in this study. The spiro[bicyclo[3.2.1]octane-pyran] core was constructed by an acid-promoted epoxide-opening lactonisation and a base-induced intramolecular aldol-type cyclisation.