Detalhe da pesquisa
1.
Elucidation of Metabolic and Disposition Pathways for Maribavir in Nonhuman Primates through Mass Balance and Semi-Physiologically Based Modeling Approaches.
Drug Metab Dispos
; 49(11): 1025-1037, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34462268
2.
Improved Protease-Targeting and Biopharmaceutical Properties of Novel Prodrugs of Ganciclovir.
Mol Pharm
; 15(2): 410-419, 2018 02 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29251944
3.
Use of cassette dosing to enhance the throughput of rat brain microdialysis studies.
Drug Metab Dispos
; 43(7): 1123-8, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25943358
4.
Maribavir: Mechanism of action, clinical, and translational science.
Clin Transl Sci
; 17(1): e13696, 2024 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38071422
5.
Effect of Food, Crushing of Tablets, and Antacid Coadministration on Maribavir Pharmacokinetics in Healthy Adult Participants: Results From 2 Phase 1, Open-Label, Randomized, Crossover Studies.
Clin Pharmacol Drug Dev
; 13(6): 644-654, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38708555
6.
Population pharmacokinetic modeling and simulation of maribavir to support dose selection and regulatory approval in adolescents with posttransplant refractory cytomegalovirus.
CPT Pharmacometrics Syst Pharmacol
; 12(5): 719-723, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36789522
7.
Physiologically Based Pharmacokinetic Modeling for Maribavir to Inform Dosing in Drug-Drug Interaction Scenarios with CYP3A4 Inducers and Inhibitors.
J Clin Pharmacol
; 2023 Nov 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38009271
8.
Model-Informed Approaches and Innovative Clinical Trial Design for Adeno-Associated Viral Vector-Based Gene Therapy Product Development: A White Paper.
Clin Pharmacol Ther
; 114(3): 515-529, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37313953
9.
PK/PD and Bioanalytical Considerations of AAV-Based Gene Therapies: an IQ Consortium Industry Position Paper.
AAPS J
; 25(5): 78, 2023 07 31.
Artigo
Inglês
| MEDLINE | ID: mdl-37523051
10.
Clinical Pharmacology Considerations on Recombinant Adeno-Associated Virus-Based Gene Therapy.
J Clin Pharmacol
; 62 Suppl 2: S79-S94, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36461742
11.
The Perspective of DMPK on Recombinant Adeno-Associated Virus-Based Gene Therapy: Past Learning, Current Support, and Future Contribution.
AAPS J
; 24(1): 31, 2022 01 31.
Artigo
Inglês
| MEDLINE | ID: mdl-35102450
12.
Prediction of Ovarian Cancer-Related Metabolites Based on Graph Neural Network.
Front Cell Dev Biol
; 9: 753221, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34676219
13.
[In vitro growth and function of neonatal cardiomyocytes in various transcatheter closure device patches].
Zhonghua Xin Xue Guan Bing Za Zhi
; 37(9): 841-4, 2009 Sep.
Artigo
Chinês
| MEDLINE | ID: mdl-20128386