Detalhe da pesquisa
1.
Mimicking CHO large-scale effects in the single multicompartment bioreactor: A new approach to access scale-up behavior.
Biotechnol Bioeng
; 121(4): 1244-1256, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38192095
2.
Synthetic co-culture in an interconnected two-compartment bioreactor system: violacein production with recombinant E. coli strains.
Bioprocess Biosyst Eng
; 47(5): 713-724, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38627303
3.
Towards valorization of pectin-rich agro-industrial residues: Engineering of Saccharomyces cerevisiae for co-fermentation of d-galacturonic acid and glycerol.
Metab Eng
; 69: 1-14, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34648971
4.
Engineering of a robust Escherichia coli chassis and exploitation for large-scale production processes.
Metab Eng
; 67: 75-87, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34098100
5.
Data-driven in silico prediction of regulation heterogeneity and ATP demands of Escherichia coli in large-scale bioreactors.
Biotechnol Bioeng
; 118(1): 265-278, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32940924
6.
Balancing glucose and oxygen uptake rates to enable high amorpha-4,11-diene production in Escherichia coli via the methylerythritol phosphate pathway.
Biotechnol Bioeng
; 118(3): 1317-1329, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33331668
7.
Pseudomonas putida KT2440 endures temporary oxygen limitations.
Biotechnol Bioeng
; 118(12): 4735-4750, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34506651
8.
Compartment-specific metabolome labeling enables the identification of subcellular fluxes that may serve as promising metabolic engineering targets in CHO cells.
Bioprocess Biosyst Eng
; 44(12): 2567-2578, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-34590184
9.
Prediction of novel non-coding RNAs relevant for the growth of Pseudomonas putida in a bioreactor.
Microbiology (Reading)
; 166(2): 149-156, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31860438
10.
Simulated oxygen and glucose gradients as a prerequisite for predicting industrial scale performance a priori.
Biotechnol Bioeng
; 117(9): 2760-2770, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32530496
11.
S-adenosylmethionine and methylthioadenosine boost cellular productivities of antibody forming Chinese hamster ovary cells.
Biotechnol Bioeng
; 117(11): 3239-3247, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32644191
12.
From nutritional wealth to autophagy: In vivo metabolic dynamics in the cytosol, mitochondrion and shuttles of IgG producing CHO cells.
Metab Eng
; 54: 145-159, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30930288
13.
Exploiting Hydrogenophaga pseudoflava for aerobic syngas-based production of chemicals.
Metab Eng
; 55: 220-230, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31319152
14.
Perfusion cultures require optimum respiratory ATP supply to maximize cell-specific and volumetric productivities.
Biotechnol Bioeng
; 116(5): 951-960, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30659583
15.
Protein production in Escherichia coli is guided by the trade-off between intracellular substrate availability and energy cost.
Microb Cell Fact
; 18(1): 8, 2019 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-30654806
16.
Metabolic engineering to guide evolution - Creating a novel mode for L-valine production with Corynebacterium glutamicum.
Metab Eng
; 47: 31-41, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29522826
17.
Escherichia coli HGT: Engineered for high glucose throughput even under slowly growing or resting conditions.
Metab Eng
; 40: 93-103, 2017 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28110078
18.
High Substrate Uptake Rates Empower Vibrio natriegens as Production Host for Industrial Biotechnology.
Appl Environ Microbiol
; 83(22)2017 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28887417
19.
Dynamic modeling reveals a three-step response of Saccharomyces cerevisiae to high CO2 levels accompanied by increasing ATP demands.
FEMS Yeast Res
; 17(1)2017 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28175306
20.
Engineering E. coli for large-scale production - Strategies considering ATP expenses and transcriptional responses.
Metab Eng
; 38: 73-85, 2016 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27378496