Detalhe da pesquisa
1.
Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms.
Xenobiotica
; 49(5): 528-539, 2019 May.
Artigo
Inglês
| MEDLINE | ID: mdl-29771166
2.
Combination of APD668, a G protein-coupled receptor 119 agonist with linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in a murine model of non-alcoholic steatohepatitis with diabetes.
Med Mol Morphol
; 52(1): 36-43, 2019 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-29959534
3.
Co-administration of APD668, a G protein-coupled receptor 119 agonist and linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in mice fed on a high trans-fat diet.
Biochem Biophys Res Commun
; 495(2): 1608-1613, 2018 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29203247
4.
In the Quest for Potent and Selective Malic Enzyme 3 Inhibitors for the Treatment of Pancreatic Ductal Adenocarcinoma.
ACS Med Chem Lett
; 14(1): 41-50, 2023 Jan 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36655126
5.
Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata.
PNAS Nexus
; 2(1): pgac297, 2023 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-36712931
6.
Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists.
Bioorg Med Chem Lett
; 22(9): 3157-62, 2012 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22487182
7.
Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists: part 2.
Bioorg Med Chem Lett
; 22(9): 3163-7, 2012 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22497763
8.
Novel pyrazole-3-carboxamide derivatives as cannabinoid-1 (CB1) antagonists: journey from non-polar to polar amides.
Bioorg Med Chem Lett
; 21(1): 562-8, 2011 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21075633
9.
Structure-activity relationship studies of novel pyrazole and imidazole carboxamides as cannabinoid-1 (CB1) antagonists.
Bioorg Med Chem Lett
; 21(16): 4913-8, 2011 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21741835
10.
Discovery of novel, orally available benzimidazoles as melanin concentrating hormone receptor 1 (MCHR1) antagonists.
Bioorg Med Chem Lett
; 20(18): 5443-8, 2010 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20724156
11.
Discovery of Potent, Selective, and State-Dependent NaV1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure-Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides.
J Med Chem
; 63(11): 6107-6133, 2020 06 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32368909
12.
Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate.
J Med Chem
; 62(23): 10563-10582, 2019 12 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31710479
13.
Evaluation of minimal residual disease in patients with chronic myeloid leukaemia on IFN-alpha 2b therapy using conventional cytogenetics and fluorescence in situ hybridization.
Natl Med J India
; 15(4): 195-8, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-12296472
14.
Differentiation of Fanconi anemia from idiopathic aplastic anemia by induced chromosomal breakage study using mitomycin-C (MMC).
Indian Pediatr
; 41(5): 473-7, 2004 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15181297
15.
Cannabinoid 1 (CB1) receptor--pharmacology, role in pain and recent developments in emerging CB1 agonists.
CNS Neurol Disord Drug Targets
; 10(5): 536-44, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21631407
16.
Complete oral rehabilitation of a young girl suffering with amelogenesis imperfecta in association with analysis of her chromosomal pattern.
BMJ Case Rep
; 20132013 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23513017
17.
Stabilization of RelB requires multidomain interactions with p100/p52.
J Biol Chem
; 283(18): 12324-32, 2008 May 02.
Artigo
Inglês
| MEDLINE | ID: mdl-18321863
18.
Inhibitor kappaB kinase beta binding by inhibitor kappaB kinase gamma.
Biochemistry
; 46(43): 12482-90, 2007 Oct 30.
Artigo
Inglês
| MEDLINE | ID: mdl-17924664
19.
A case of chronic myeloid leukemia complicated with minimal change nephrotic syndrome.
Acta Haematol
; 109(2): 101-3, 2003.
Artigo
Inglês
| MEDLINE | ID: mdl-12624495
20.
Human molecular cytogenetics: diagnosis, prognosis, and disease management.
Teratog Carcinog Mutagen
; Suppl 1: 225-33, 2003.
Artigo
Inglês
| MEDLINE | ID: mdl-12616613