Detalhe da pesquisa
1.
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Nature
; 615(7953): 678-686, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36922586
2.
Virology analyses of HCV isolates from genotype 1-infected patients treated with simeprevir plus peginterferon/ribavirin in Phase IIb/III studies.
J Hepatol
; 62(5): 1008-14, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25445400
3.
Simeprevir (TMC435) with pegylated interferon/ribavirin in patients coinfected with HCV genotype 1 and HIV-1: a phase 3 study.
Clin Infect Dis
; 59(11): 1579-87, 2014 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25192745
4.
Sensitive testing of plasma HIV-1 RNA and Sanger sequencing of cellular HIV-1 DNA for the detection of drug resistance prior to starting first-line antiretroviral therapy with etravirine or efavirenz.
J Antimicrob Chemother
; 69(4): 1090-7, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24284781
5.
Evolution of inflammation and immunity in a dengue virus 1 human infection model.
Sci Transl Med
; 14(668): eabo5019, 2022 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-36288280
6.
Connection domain mutations in HIV-1 reverse transcriptase do not impact etravirine susceptibility and virologic responses to etravirine-containing regimens.
Antimicrob Agents Chemother
; 55(6): 2872-9, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21464253
7.
Etravirine in treatment-experienced HIV-1-infected children 1 year to less than 6 years of age.
AIDS
; 35(9): 1413-1421, 2021 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33831904
8.
Compilation and prevalence of mutations associated with resistance to non-nucleoside reverse transcriptase inhibitors.
Antivir Ther
; 14(1): 103-9, 2009.
Artigo
Inglês
| MEDLINE | ID: mdl-19320243
9.
Etravirine combined with antiretrovirals other than darunavir/ritonavir for HIV-1-infected, treatment-experienced adults: Week 48 results of a phase IV trial.
SAGE Open Med
; 5: 2050312116686482, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28382208
10.
Assessment of etravirine resistance in HIV-1-infected paediatric patients using population and deep sequencing: final results of the PIANO study.
Antivir Ther
; 21(4): 317-27, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-26566161
11.
Discovery of 1-((2R,4aR,6R,7R,7aR)-2-Isopropoxy-2-oxidodihydro-4H,6H-spiro[furo[3,2-d][1,3,2]dioxaphosphinine-7,2'-oxetan]-6-yl)pyrimidine-2,4(1H,3H)-dione (JNJ-54257099), a 3'-5'-Cyclic Phosphate Ester Prodrug of 2'-Deoxy-2'-Spirooxetane Uridine Triphosphate Useful for HCV Inhibition.
J Med Chem
; 59(12): 5790-8, 2016 06 23.
Artigo
Inglês
| MEDLINE | ID: mdl-27181575
12.
Pharmacokinetics of Etravirine Combined with Atazanavir/Ritonavir and a Nucleoside Reverse Transcriptase Inhibitor in Antiretroviral Treatment-Experienced, HIV-1-Infected Patients.
AIDS Res Treat
; 2015: 938628, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25664185
13.
Week 48 results of a Phase IV trial of etravirine with antiretrovirals other than darunavir/ritonavir in HIV-1-infected treatment-experienced adults.
J Int AIDS Soc
; 17(4 Suppl 3): 19783, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-25397527
14.
Similar predictions of etravirine sensitivity regardless of genotypic testing method used: comparison of available scoring systems.
Antivir Ther
; 17(8): 1571-9, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22869341
15.
Short communication prevalence of susceptibility to etravirine by genotype and phenotype in samples received for routine HIV type 1 resistance testing in the United States.
AIDS Res Hum Retroviruses
; 27(12): 1271-5, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21557669
16.
Effect of mutations at position E138 in HIV-1 reverse transcriptase on phenotypic susceptibility and virologic response to etravirine.
J Acquir Immune Defic Syndr
; 58(1): 18-22, 2011 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21637112
17.
Etravirine limits the emergence of darunavir and other protease inhibitor resistance-associated mutations in the DUET trials.
AIDS
; 24(6): 921-4, 2010 Mar 27.
Artigo
Inglês
| MEDLINE | ID: mdl-20160633
18.
Characterization of genotypic and phenotypic changes in HIV-1-infected patients with virologic failure on an etravirine-containing regimen in the DUET-1 and DUET-2 clinical studies.
AIDS Res Hum Retroviruses
; 26(11): 1197-205, 2010 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-20854144
19.
Resistance profile of etravirine: combined analysis of baseline genotypic and phenotypic data from the randomized, controlled Phase III clinical studies.
AIDS
; 24(4): 503-14, 2010 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-20051805
20.
Short communication: activity of etravirine on different HIV type 1 subtypes: in vitro susceptibility in treatment-naive patients and week 48 pooled DUET study data.
AIDS Res Hum Retroviruses
; 26(6): 621-4, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20507207