Detalhe da pesquisa
1.
Effects of body size and gender on the population pharmacokinetics of artesunate and its active metabolite dihydroartemisinin in pediatric malaria patients.
Antimicrob Agents Chemother
; 57(12): 5889-900, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24041884
2.
Population PK and PD Analysis of Domagrozumab in Pediatric Patients with Duchenne Muscular Dystrophy.
Clin Pharmacol Ther
; 112(6): 1291-1302, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36104012
3.
Pharmacokinetics of oral moxidectin in individuals with Onchocerca volvulus infection.
PLoS Negl Trop Dis
; 16(3): e0010005, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35333880
4.
Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects.
Malar J
; 8: 304, 2009 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-20021657
5.
PF-04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo-Controlled Study.
Clin Transl Sci
; 12(2): 180-188, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30597771
6.
A 4-week study assessing the pharmacokinetics, pharmacodynamics, safety, and tolerability of the glucagon receptor antagonist PF-06291874 administered as monotherapy in subjects with type 2 diabetes mellitus.
Diabetes Res Clin Pract
; 126: 95-104, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-28237861
7.
Discovery of efficacious Pseudomonas aeruginosa-targeted siderophore-conjugated monocarbams by application of a semi-mechanistic pharmacokinetic/pharmacodynamic model.
J Med Chem
; 58(5): 2195-205, 2015 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-25658376
8.
Model-based drug discovery: implementation and impact.
Drug Discov Today
; 18(15-16): 764-75, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23726890