Detalhe da pesquisa
1.
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts.
Proc Natl Acad Sci U S A
; 111(12): 4449-54, 2014 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-24591605
2.
Fluorescence Turn-On Folding Sensor To Monitor Proteome Stress in Live Cells.
J Am Chem Soc
; 137(35): 11303-11, 2015 Sep 09.
Artigo
Inglês
| MEDLINE | ID: mdl-26305239
3.
De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J Am Chem Soc
; 136(38): 13102-5, 2014 Sep 24.
Artigo
Inglês
| MEDLINE | ID: mdl-25209927
4.
Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-ß-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease.
Biochemistry
; 50(49): 10647-57, 2011 Dec 13.
Artigo
Inglês
| MEDLINE | ID: mdl-22047104
5.
ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.
Chem Biol
; 21(8): 967-76, 2014 Aug 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25126989
6.
FKBP10 depletion enhances glucocerebrosidase proteostasis in Gaucher disease fibroblasts.
Chem Biol
; 20(3): 403-15, 2013 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23434032