Detalhe da pesquisa
1.
Botulinum Neurotoxin A4 Has a 1000-Fold Reduced Potency Due to Three Single Amino Acid Alterations in the Protein Receptor Binding Domain.
Int J Mol Sci
; 24(6)2023 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36982762
2.
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease.
Int J Mol Sci
; 24(5)2023 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36901734
3.
Resolution of Two Steps in Botulinum Neurotoxin Serotype A1 Light Chain Localization to the Intracellular Plasma Membrane.
Int J Mol Sci
; 22(20)2021 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34681775
4.
Metal Ions Effectively Ablate the Action of Botulinum Neurotoxin A.
J Am Chem Soc
; 139(21): 7264-7272, 2017 05 31.
Artigo
Inglês
| MEDLINE | ID: mdl-28475321
5.
A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin.
J Infect Dis
; 213(3): 379-85, 2016 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26068781
6.
Multiple domains of tetanus toxin direct entry into primary neurons.
Traffic
; 15(10): 1057-65, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25040808
7.
Widespread sequence variations in VAMP1 across vertebrates suggest a potential selective pressure from botulinum neurotoxins.
PLoS Pathog
; 10(7): e1004177, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25010769
8.
Immunoprecipitation of native botulinum neurotoxin complexes from Clostridium botulinum subtype A strains.
Appl Environ Microbiol
; 81(2): 481-91, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25362065
9.
Entry of a recombinant, full-length, atoxic tetanus neurotoxin into Neuro-2a cells.
Infect Immun
; 82(2): 873-81, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24478100
10.
Comparison of the catalytic properties of the botulinum neurotoxin subtypes A1 and A5.
Biochim Biophys Acta
; 1834(12): 2722-8, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24096023
11.
Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins.
J Cell Sci
; 125(Pt 13): 3233-42, 2012 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22454523
12.
Holotoxin Activity of Botulinum Neurotoxin Subtype A4 Originating from a Nontoxigenic Clostridium botulinum Expression System.
Appl Environ Microbiol
; 80(23): 7415-22, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25239905
13.
Botulinum neurotoxin X lacks potency in mice and in human neurons.
mBio
; 15(3): e0310623, 2024 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38347673
14.
Enhancing the protective immune response against botulism.
Infect Immun
; 81(7): 2638-44, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23670557
15.
Characterization of botulinum neurotoxin A subtypes 1 through 5 by investigation of activities in mice, in neuronal cell cultures, and in vitro.
Infect Immun
; 81(10): 3894-902, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23918782
16.
Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
PLoS Pathog
; 7(3): e1002008, 2011 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-21483489
17.
Association of toxin-producing Clostridium botulinum with the macroalga Cladophora in the Great Lakes.
Environ Sci Technol
; 47(6): 2587-94, 2013 Mar 19.
Artigo
Inglês
| MEDLINE | ID: mdl-23421373
18.
Botulinum neurotoxins B and E translocate at different rates and exhibit divergent responses to GT1b and low pH.
Biochemistry
; 51(28): 5655-62, 2012 Jul 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22720883
19.
Model for studying Clostridium botulinum neurotoxin using differentiated motor neuron-like NG108-15 cells.
Biochem Biophys Res Commun
; 427(2): 426-30, 2012 Oct 19.
Artigo
Inglês
| MEDLINE | ID: mdl-23000406
20.
SV2 mediates entry of tetanus neurotoxin into central neurons.
PLoS Pathog
; 6(11): e1001207, 2010 Nov 24.
Artigo
Inglês
| MEDLINE | ID: mdl-21124874