Detalhe da pesquisa
1.
The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model.
Glia
; 70(6): 1117-1132, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35174546
2.
Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.
Acta Neuropathol
; 137(4): 599-617, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30721409
3.
Tau Interacting Proteins: Gaining Insight into the Roles of Tau in Health and Disease.
Adv Exp Med Biol
; 1184: 145-166, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-32096036
4.
Combined treatment with a BACE inhibitor and anti-Aß antibody gantenerumab enhances amyloid reduction in APPLondon mice.
J Neurosci
; 34(35): 11621-30, 2014 Aug 27.
Artigo
Inglês
| MEDLINE | ID: mdl-25164658
5.
Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.
J Neurosci
; 34(26): 8845-54, 2014 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-24966384
6.
Extracellular phosphorylation of the amyloid ß-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.
EMBO J
; 30(11): 2255-65, 2011 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21527912
7.
Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.
Acta Neuropathol
; 129(6): 875-94, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25862635
8.
Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Proc Natl Acad Sci U S A
; 107(13): 6058-63, 2010 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-20231476
9.
Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aß phagocytosis.
J Neurosci
; 31(19): 7049-59, 2011 May 11.
Artigo
Inglês
| MEDLINE | ID: mdl-21562267
10.
Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease.
J Neurochem
; 118(1): 105-12, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-21517843
11.
Restraint stress increases neuroinflammation independently of amyloid ß levels in amyloid precursor protein/PS1 transgenic mice.
J Neurochem
; 116(1): 43-52, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-21044080
12.
NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits.
J Neurosci
; 29(45): 14177-84, 2009 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-19906966
13.
Serine-409 phosphorylation and oxidative damage define aggregation of human protein tau in yeast.
FEMS Yeast Res
; 10(8): 992-1005, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-20662935
14.
Neuroinflammatory processes in Alzheimer's disease.
J Neural Transm (Vienna)
; 117(8): 919-47, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-20632195
15.
PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models.
J Neurochem
; 109(6): 1779-90, 2009 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-19457135
16.
Tau-4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice.
FASEB J
; 21(9): 2149-61, 2007 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-17341679
17.
Improved long-term potentiation and memory in young tau-P301L transgenic mice before onset of hyperphosphorylation and tauopathy.
J Neurosci
; 26(13): 3514-23, 2006 Mar 29.
Artigo
Inglês
| MEDLINE | ID: mdl-16571759
18.
Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on ß-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease.
PLoS One
; 11(7): e0158205, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27421117
19.
The GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy.
Brain Res
; 1634: 158-170, 2016 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26746341
20.
CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model.
J Clin Invest
; 125(1): 365-78, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25500888