Detalhe da pesquisa
1.
Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring.
Bioorg Med Chem Lett
; 22(10): 3392-7, 2012 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22542194
2.
SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.
J Biol Chem
; 285(11): 8340-51, 2010 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-20061378
3.
Design of a multi-purpose fragment screening library using molecular complexity and orthogonal diversity metrics.
J Comput Aided Mol Des
; 25(7): 621-36, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-21604056
4.
Aminopyrazole Carboxamide Bruton's Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning.
ACS Med Chem Lett
; 10(1): 80-85, 2019 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30655951
5.
Phosphopantetheine adenylyltransferase from Escherichia coli: investigation of the kinetic mechanism and role in regulation of coenzyme A biosynthesis.
J Bacteriol
; 189(22): 8196-205, 2007 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-17873050
6.
Determination of tacrine metabolites in microsomal incubate by high performance liquid chromatography-nuclear magnetic resonance/mass spectrometry with a column trapping system.
J Pharm Biomed Anal
; 28(1): 23-30, 2002 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-11861105
7.
The use of biochemical and biophysical tools for triage of high-throughput screening hits - A case study with Escherichia coli phosphopantetheine adenylyltransferase.
Chem Biol Drug Des
; 75(5): 444-54, 2010 May.
Artigo
Inglês
| MEDLINE | ID: mdl-20486930
8.
Discovery of antibacterial biotin carboxylase inhibitors by virtual screening and fragment-based approaches.
ACS Chem Biol
; 4(6): 473-83, 2009 Jun 19.
Artigo
Inglês
| MEDLINE | ID: mdl-19413326