1.
Cephalalgia
; 8(4): 269-72, 1988 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3064919
RESUMO
Nimodipine is a compound that is thought to block the influx of calcium through channels in vascular smooth muscle. This paper describes a double-blind parallel-group comparison of 40 mg nimodipine three times a day and placebo. Sixty-eight patients received treatment after a run-in period of 2 months, and of these, 57 completed 8 weeks or more of the trial. All but five of these completed the full 6-month trial. The nimodipine and placebo groups showed no significant differences in the frequency of attacks, severity or duration of headache, or gastrointestinal or other symptoms.
Assuntos
Transtornos de Enxaqueca/prevenção & controle , Nimodipina/uso terapêutico , Adolescente , Adulto , Ensaios Clínicos como Assunto , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Distribuição Aleatória
2.
Headache
; 28(7): 481-3, 1988 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3243710