Detalhe da pesquisa
1.
Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency.
Cell
; 160(6): 1072-86, 2015 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-25768904
2.
Transfer learning enables predictions in network biology.
Nature
; 618(7965): 616-624, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37258680
3.
MIRA: joint regulatory modeling of multimodal expression and chromatin accessibility in single cells.
Nat Methods
; 19(9): 1097-1108, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36068320
4.
NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium.
J Mol Cell Cardiol
; 84: 13-23, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25871831
5.
Race, Ethnicity, and Ancestry in Clinical Pathways: A Framework for Evaluation.
Pediatrics
; 152(6)2023 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37974460
6.
Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease.
Science
; 371(6530)2021 02 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33303684
7.
Interpretable model of CRISPR-Cas9 enzymatic reactions.
Nat Comput Sci
; 3(12): 1011-1012, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-38177728
8.
Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency.
J Clin Invest
; 127(5): 1683-1688, 2017 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28346225
9.
The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling.
Stem Cell Res Ther
; 7(1): 115, 2016 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-27530160