Detalhe da pesquisa
1.
2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses.
Proc Natl Acad Sci U S A
; 120(42): e2304139120, 2023 10 17.
Artigo
Inglês
| MEDLINE | ID: mdl-37831739
2.
Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses.
Proc Natl Acad Sci U S A
; 119(36): e2206104119, 2022 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36037386
3.
Isolation and Characterization of Distinct Rotavirus A in Bat and Rodent Hosts.
J Virol
; 97(1): e0145522, 2023 01 31.
Artigo
Inglês
| MEDLINE | ID: mdl-36633410
4.
SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells.
PLoS Pathog
; 17(1): e1009233, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33476327
5.
Structure-activity relationship studies of anti-bunyaviral cap-dependent endonuclease inhibitors.
Bioorg Med Chem Lett
; 83: 129175, 2023 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36758821
6.
Serological characterization of lineage II insect-specific flaviviruses compared with pathogenic mosquito-borne flaviviruses.
Biochem Biophys Res Commun
; 616: 115-121, 2022 08 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35665607
7.
Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model.
J Antimicrob Chemother
; 77(11): 2984-2991, 2022 10 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35914182
8.
Air-liquid interphase culture confers SARS-CoV-2 susceptibility to A549 alveolar epithelial cells.
Biochem Biophys Res Commun
; 577: 146-151, 2021 11 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34517212
9.
In Vivo Pharmacodynamic Study of Cefiderocol, a Novel Parenteral Siderophore Cephalosporin, in Murine Thigh and Lung Infection Models.
Antimicrob Agents Chemother
; 63(9)2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31262762
10.
In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacteria.
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29061741
11.
Viral uptake and pathophysiology of the lung endothelial cells in age-associated severe SARS-CoV-2 infection models.
Aging Cell
; 23(2): e14050, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38098255
12.
Immunogenicity and protective efficacy of a co-formulated two-in-one inactivated whole virus particle COVID-19/influenza vaccine.
Sci Rep
; 14(1): 4204, 2024 02 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38378856
13.
Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in a COVID-19 hamster model.
EBioMedicine
; 99: 104950, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38159532
14.
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
Sci Transl Med
; 15(679): eabq4064, 2023 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36327352
15.
[In vitro activity of doripenem against strains from pediatric diseases and strains causing purulent meningitis].
Jpn J Antibiot
; 65(6): 381-98, 2012 Dec.
Artigo
Japonês
| MEDLINE | ID: mdl-23593734
16.
Characterization of the In Vitro and In Vivo Efficacy of Baloxavir Marboxil against H5 Highly Pathogenic Avian Influenza Virus Infection.
Viruses
; 14(1)2022 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35062315
17.
Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease.
J Med Chem
; 65(20): 13852-13865, 2022 10 27.
Artigo
Inglês
| MEDLINE | ID: mdl-36229406
18.
Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19.
J Med Chem
; 65(9): 6499-6512, 2022 05 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35352927
19.
[In vitro combination effects of doripenem with aminoglycoside or ciprofloxacin against Pseudomonas aeruginosa].
Jpn J Antibiot
; 64(4): 203-16, 2011 Aug.
Artigo
Japonês
| MEDLINE | ID: mdl-22066345
20.
MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2.
Sci Rep
; 11(1): 5376, 2021 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33686154