Detalhe da pesquisa
1.
Targeted genetic therapies for inherited disorders that affect both cardiac and skeletal muscle.
Exp Physiol
; 109(2): 175-189, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38095849
2.
Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes.
J Mol Cell Cardiol
; 180: 44-57, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37127261
3.
Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation.
Circ Res
; 129(7): 751-766, 2021 09 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34405687
4.
CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.
Circ Res
; 129(2): 326-341, 2021 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34018815
5.
Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.
Circulation
; 141(10): 828-842, 2020 03 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31983222
6.
Novel Therapies for Prevention and Early Treatment of Cardiomyopathies.
Circ Res
; 124(11): 1536-1550, 2019 05 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31120825
8.
Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy.
Circulation
; 140(1): 31-41, 2019 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30987448
9.
Revisiting Frank-Starling: regulatory light chain phosphorylation alters the rate of force redevelopment (ktr ) in a length-dependent fashion.
J Physiol
; 594(18): 5237-54, 2016 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27291932
10.
A post-MI power struggle: adaptations in cardiac power occur at the sarcomere level alongside MyBP-C and RLC phosphorylation.
Am J Physiol Heart Circ Physiol
; 311(2): H465-75, 2016 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27233767
11.
Power output of skinned skeletal muscle fibres from the cheetah (Acinonyx jubatus).
J Exp Biol
; 216(Pt 15): 2974-82, 2013 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23580727
12.
Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation.
Front Cell Infect Microbiol
; 13: 1098457, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36814444
13.
Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy.
Sci Rep
; 12(1): 22501, 2022 12 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36577774
14.
Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome.
iScience
; 25(1): 103596, 2022 Jan 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34988410
15.
Cardiac myosin super relaxation (SRX): a perspective on fundamental biology, human disease and therapeutics.
Biol Open
; 10(2)2021 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33589442
16.
Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization.
Sci Adv
; 7(42): eabh3995, 2021 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34652945
17.
GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm.
Elife
; 92020 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33054971
18.
Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients.
Circ Genom Precis Med
; 13(5): 424-434, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32815737
19.
Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.
Sci Transl Med
; 11(476)2019 01 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30674652
20.
Differentiation and Contractile Analysis of GFP-Sarcomere Reporter hiPSC-Cardiomyocytes.
Curr Protoc Hum Genet
; 96: 21.12.1-21.12.12, 2018 01 24.
Artigo
Inglês
| MEDLINE | ID: mdl-29364522