Detalhe da pesquisa
1.
Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.
Proc Natl Acad Sci U S A
; 112(50): E6993-7002, 2015 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26621731
2.
ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS.
Proc Natl Acad Sci U S A
; 107(30): 13318-23, 2010 Jul 27.
Artigo
Inglês
| MEDLINE | ID: mdl-20624952
3.
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.
Elife
; 82019 02 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30747709
4.
ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.
Nat Commun
; 6: 6171, 2015 Jan 27.
Artigo
Inglês
| MEDLINE | ID: mdl-25625564
5.
Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy.
Neuron
; 82(2): 295-307, 2014 Apr 16.
Artigo
Inglês
| MEDLINE | ID: mdl-24742458