Detalhe da pesquisa
1.
Nuclear accumulation of host transcripts during Zika Virus Infection.
PLoS Pathog
; 19(1): e1011070, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36603024
2.
Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies.
Pharm Res
; 38(12): 2129-2145, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-34904202
3.
Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.
J Biol Chem
; 290(32): 19403-22, 2015 Aug 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26055715
4.
Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4--The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS).
Bioorg Med Chem
; 23(17): 6036-48, 2015 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26190463
5.
Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity.
J Virol
; 87(23): 12611-8, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24027335
6.
Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding.
Bioorg Med Chem Lett
; 23(22): 6172-7, 2013 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24080461
7.
Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors.
Mol Cancer Ther
; 21(7): 1195-1206, 2022 07 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35499461
8.
Cocrystals of diacerein: Towards the development of improved biopharmaceutical parameters.
Int J Pharm
; 574: 118942, 2020 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31830577
9.
Crystallization and preliminary X-ray diffraction analysis of the complex of Kunitz-type tamarind trypsin inhibitor and porcine pancreatic trypsin.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 65(Pt 11): 1179-81, 2009 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19923745
10.
Low expression of RNA sensors impacts Zika virus infection in the lower female reproductive tract.
Nat Commun
; 10(1): 4344, 2019 09 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31554802
11.
A BAF'ling Approach to Curing HIV.
Cell Chem Biol
; 25(12): 1441-1442, 2018 12 20.
Artigo
Inglês
| MEDLINE | ID: mdl-30576660
12.
The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein.
mBio
; 9(6)2018 11 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30401782
13.
A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant.
mBio
; 5(2): e00047-14, 2014 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-24667706
14.
Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease.
J Med Chem
; 56(2): 534-46, 2013 Jan 24.
Artigo
Inglês
| MEDLINE | ID: mdl-23231439
15.
Structure-function studies of DNA binding domain of response regulator KdpE reveals equal affinity interactions at DNA half-sites.
PLoS One
; 7(1): e30102, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22291906