Detalhe da pesquisa
1.
mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species.
Nat Metab
; 4(12): 1792-1811, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36536136
2.
The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth.
Cell Rep
; 39(7): 110824, 2022 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35584673
3.
Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex.
iScience
; 25(11): 105458, 2022 Nov 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36388985
4.
The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals.
Elife
; 102021 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33646118
5.
IMPDH inhibitors for antitumor therapy in tuberous sclerosis complex.
JCI Insight
; 5(7)2020 04 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32271165
6.
Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.
Nat Commun
; 8: 16031, 2017 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28685754
7.
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Science
; 353(6304): 1161-5, 2016 09 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27609895
8.
Circulating Metabolites and Survival Among Patients With Pancreatic Cancer.
J Natl Cancer Inst
; 108(6): djv409, 2016 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-26755275
9.
Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.
Nat Med
; 20(10): 1193-1198, 2014 10.
Artigo
Inglês
| MEDLINE | ID: mdl-25261994