Detalhe da pesquisa
1.
An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping.
Cell
; 183(5): 1420-1435.e21, 2020 11 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33159857
2.
Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis.
Cell
; 174(4): 856-869.e17, 2018 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30096312
3.
An organoid-based organ-repurposing approach to treat short bowel syndrome.
Nature
; 592(7852): 99-104, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33627870
4.
Somatic inflammatory gene mutations in human ulcerative colitis epithelium.
Nature
; 577(7789): 254-259, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31853059
5.
Organoid screening reveals epigenetic vulnerabilities in human colorectal cancer.
Nat Chem Biol
; 18(6): 605-614, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35273398
6.
Identification of Quiescent LGR5+ Stem Cells in the Human Colon.
Gastroenterology
; 163(5): 1391-1406.e24, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35963362
7.
Chromosome Engineering of Human Colon-Derived Organoids to Develop a Model of Traditional Serrated Adenoma.
Gastroenterology
; 158(3): 638-651.e8, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31622618
8.
Silencing of microRNA-122 is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis.
Cancer Sci
; 105(10): 1254-60, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25117675
9.
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency.
NPJ Precis Oncol
; 8(1): 117, 2024 May 24.
Artigo
Inglês
| MEDLINE | ID: mdl-38789724
10.
Delivery of a BET protein degrader via a CEACAM6-targeted antibody-drug conjugate inhibits tumour growth in pancreatic cancer models.
Nat Commun
; 15(1): 2192, 2024 Mar 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38467634
11.
Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma.
Cell Rep
; 42(3): 112212, 2023 03 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36870059
12.
Direct derivation of human alveolospheres for SARS-CoV-2 infection modeling and drug screening.
Cell Rep
; 35(10): 109218, 2021 06 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34038715
13.
Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition.
Cell Stem Cell
; 23(6): 787-793.e6, 2018 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30526881
14.
Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression.
Cell Stem Cell
; 22(3): 454-467.e6, 2018 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29337182
15.
Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response.
Sci Rep
; 6: 25311, 2016 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-27143627
16.
A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis.
Cell Stem Cell
; 18(6): 827-838, 2016 06 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27212702