RESUMO
INTRODUCTION: Fahr's syndrome is characterized by symmetrical and bilateral intracerebral calcifications, located in the basal ganglia and mostly associated with a phosphorus calcium metabolism disorder. It must be distinguished from genetic or sporadic Fahr's disease. OBSERVATIONS: We report two cases of this syndrome, the first was revealed by psychotic and cognitive disorders and the other by epilepsy. In both cases, brain imaging and biology resulted in the diagnosis of Fahr's syndrome. The outcome was favorable after treatment in both cases. CONCLUSION: These two observations illustrate various clinical signs of Fahr's syndrome.
Assuntos
Doenças dos Gânglios da Base/diagnóstico por imagem , Doenças dos Gânglios da Base/psicologia , Calcinose/diagnóstico por imagem , Calcinose/psicologia , Distúrbios do Metabolismo do Cálcio/diagnóstico por imagem , Distúrbios do Metabolismo do Cálcio/psicologia , Adulto , Idoso , Doenças dos Gânglios da Base/terapia , Calcinose/terapia , Cálcio/uso terapêutico , Distúrbios do Metabolismo do Cálcio/terapia , Transtornos Cognitivos/etiologia , Transtornos Cognitivos/psicologia , Feminino , Humanos , Masculino , Transtornos Psicóticos/etiologia , Síndrome , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Vitamina B 12/uso terapêutico , Vitamina D/uso terapêuticoRESUMO
BACKGROUND: The periarteritis nodosa (PAN) is a serious necrotizing vasculitis. Healing is, classically, obtained after a long-term treatment using corticosteroids and immunosuppressive agents. PURPOSE: Reporting the case of a NAP or was spontaneous healing without having recourse to any immunosuppressive treatment. CASE REPORT: We report an observation of a patient aged 27 monitoring for manic-depressive psychosis hospitalized for a fever during the course associated with high blood pressure (hypertension), a weight loss, asthenia and myalgia. Biology was a biological inflammatory syndrome (SIB), a creatinine 115 micromol/l. The survey infectious and immunological balance were negative. The arteriography showed a strongly evocative of the NAP. We have seen no sign of poor prognosis. The recovery was spontaneous after a short period of evolution with an amendment clinical and biological weapons. The patient was put under anti-HTA and reviewed regularly to the consultation. CONCLUSION: An analogy is drawn between such developments and already reported in some cases of viral PAN. The actual frequency of self-limitting PAN is unknown. The scarcity of cases reported in the literature may in part be attributed to ignorance.
Assuntos
Poliarterite Nodosa/diagnóstico , Adulto , Humanos , Masculino , Remissão EspontâneaRESUMO
Kawasaki disease (KD) is a multisystemic vasculitis disorder in children. The dermatological manifestations are described as polymorphic and nonspecific. However, they are important for diagnosis. They correspond to 3 out of the 5 major criteria that may be associated with the disease's constant fever. We report the case of a child aged 3 years 8 months who showed necrotic lesions on the cheeks and the nose, associated with an erythematous, macular eruption on the rest of the body. Necrotic lesions have been exceptionally reported. These misleading cutaneous aspects should not delay or rule out the diagnosis of KD, especially in atypical or incomplete forms. Early diagnosis of KD should be made before the onset of coronary lesions.