Detalhe da pesquisa
1.
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma.
Nat Immunol
; 22(7): 851-864, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34099918
2.
Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity.
Nat Immunol
; 21(8): 914-926, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32424363
3.
Untimely TGFß responses in COVID-19 limit antiviral functions of NK cells.
Nature
; 600(7888): 295-301, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34695836
4.
A cell-based functional assay that accurately links genotype to phenotype in familial HLH.
Blood
; 141(19): 2330-2342, 2023 05 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36706356
5.
Natural killer cells kill extracellular Pseudomonas aeruginosa using contact-dependent release of granzymes B and H.
PLoS Pathog
; 18(2): e1010325, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35202434
6.
Severely impaired CTL killing is a feature of the neurological disorder Niemann-Pick disease type C1.
Blood
; 139(12): 1833-1849, 2022 03 24.
Artigo
Inglês
| MEDLINE | ID: mdl-35081253
7.
CD8+ T Cells Promote Pathological Angiogenesis in Ocular Neovascular Disease.
Arterioscler Thromb Vasc Biol
; 43(4): 522-536, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36794587
8.
The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells.
Haematologica
; 108(1): 83-97, 2023 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35770527
9.
TRAIL+ NK cells control CD4+ T cell responses during chronic viral infection to limit autoimmunity.
Immunity
; 41(4): 646-56, 2014 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25367576
10.
CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity.
Nature
; 549(7670): 101-105, 2017 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28813417
11.
Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies.
J Immunol
; 204(8): 2308-2315, 2020 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32152070
12.
PVRIG is a novel natural killer cell immune checkpoint receptor in acute myeloid leukemia
Haematologica
; 106(12): 3115-3124, 2021 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33147937
13.
Lipid specificity of the immune effector perforin.
Faraday Discuss
; 232(0): 236-255, 2021 12 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34545865
14.
Protection from endogenous perforin: glycans and the C terminus regulate exocytic trafficking in cytotoxic lymphocytes.
Immunity
; 34(6): 879-92, 2011 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-21658975
15.
Regulation of perforin activation and pre-synaptic toxicity through C-terminal glycosylation.
EMBO Rep
; 18(10): 1775-1785, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28808112
16.
Antigen-specific CD4+ CD25+ T cells induced by locally expressed ICOS-Ig: the role of Foxp3, Perforin, Granzyme B and IL-10 - an experimental study.
Transpl Int
; 32(11): 1203-1215, 2019 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-31225919
17.
The molecular basis for perforin oligomerization and transmembrane pore assembly.
Immunity
; 30(5): 684-95, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-19446473
18.
Conformational changes during pore formation by the perforin-related protein pleurotolysin.
PLoS Biol
; 13(2): e1002049, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25654333
19.
Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.
J Biol Chem
; 291(36): 18740-52, 2016 09 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27385590
20.
Prevalence and disease predisposition of p.A91V perforin in an aged population of European ancestry.
Blood
; 135(8): 582-584, 2020 02 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31932842