Effects of mirror-box therapy on modulation of sensorimotor EEG oscillatory rhythms: a single-case longitudinal study.

We provide direct electrophysiological evidence that mirror therapy (MT) can change brain activity and aid in the recovery of motor function after stroke. In this longitudinal single-case study, the subject was a 58-yr-old man with right-hand hemiplegia due to ischemic stroke. Over a 9-mo period we treated him with MT twice a week and measured electroencephalograms (EEG) before, during, and after each therapy session. Using advanced signal processing methods, we identified five distinct movement-related oscillatory EEG components: one slow component designated as mu rhythm and four faster components designated as sensorimotor rhythms. Results show that MT produced long-term changes of two oscillatory EEG components including the mu rhythm, which is a well-documented correlate of voluntary movement in the frequency range of 7.5-12 Hz. Specifically, MT was significantly associated with an increase in the power of mu rhythm recorded over both hemispheres and a decrease in the power of one sensorimotor component recorded over the affected hemisphere. To obtain robust, repeatable individual measures of EEG components suitable for longitudinal study, we used irregular-resampling autospectral analysis to separate fractal and oscillatory components in the EEG power spectrum and three-way parallel factor analysis to isolate oscillatory EEG components and track their activations over time. The rhythms were identified over individual days of MT training and were clearly related to the periods of event-related desynchronization and synchronization (rest, observe, and move) during MT. Our results are consistent with a model in which MT promotes recovery of motor function by altering neural activity associated with voluntary movement. NEW & NOTEWORTHY We provide novel evidence that mirror therapy (MT), which helps in the recovery of motor function after a stroke, is also associated with long-lasting changes in brain electrical activity. Using precise measurements of oscillatory EEG components over a 9-mo period in a victim of ischemic stroke, we showed that MT produced long-term increases in the mu rhythm recorded over both hemispheres and a decrease in a sensorimotor EEG component recorded over the affected hemisphere.

[A NOVEL GENDER-SPECIFIC VEST FOR FEMALE INFANTRY RECRUITS DOES NOT REDUCE THE INCIDENCE OF OVERUSE PAIN SYNDROMES: A PROSPECTIVE RANDOMIZED STUDY AMONG 240 RECRUITS].

INTRODUCTION: Overuse pain syndromes constitute a troublesome byproduct of military infantry training, particularly in female fighters. These injuries result in lost days of training, pain and discomfort and can affect fitness and fighting abilities. We hypothesized that a gender specific vest would reduce the incidence of overuse pain syndromes in a population of female recruits during basic training. OBJECTIVE: The purpose of this study was therefore to examine the effect of a novel gender-specific combat vest on the incidence of lower back pain (LBP), anterior knee pain syndrome (AKPS), and plantar heel foot pain (PHFP) among female recruits. MATERIAL AND METHODS: A prospective randomized study was conducted among 243 female border police infantry recruits who were followed over 4-months of basic training. In this group, 101 females were equipped with standard unisex special unit fighting vest (SUFV) and compared to 139 females who were equipped with a novel well-padded new fighting vest (NFV), specifically designed to fit the upper body morphology of females. This novel vest was supplied in three sizes, and equipped with adjustable straps. Information regarding the occurrence of overuse injuries was collected every two weeks. Medical records and clinic visits were evaluated. Attention was given to complaints of low back pain (LBP), anterior knee pain (AKP) and plantar heel foot pain (PHFP). RESULTS: Two hundred and forty recruits completed the study. Three recruits were lost to follow-up. Anterior knee pain was recorded in 65% of recruits in the SUFV group versus 62% in the NFV group (p = ns). Lower back pain was recorded in 86% of the SUFV group versus 82% in the NFV group (p = ns), and plantar heel foot pain was recorded in 73% of the SUFV group versus 69% in the NFV group (p = ns). DISCUSSION: Overuse pain injuries are more commonly reported among female fighters. These injuries result in lost days of training, pain and discomfort and can affect combat ability. Several researchers have found that changes in fighting equipment, such as size and weight, can affect the rates of these injuries. There is still a lack of information regarding changes related to gender-based fighting equipment and their effects. CONCLUSION: A gender-specific combat vest, designed to fit the upper female body, did not have any protective effect on the occurrence of overuse pain syndromes of the back, knee and foot in this study. It seems that in order to reduce the incidence of these injuries in female recruits, emphasis should be directed at other factors such as modifications in equipment weight, as well as modifications in the intensity of the training programs.

Tensor decomposition of human narrowband oscillatory brain activity in frequency, space and time.

Many brain processes in health and disease are associated with modulation of narrowband brain oscillations (NBOs) in the scalp-recorded EEG, which exhibit specific frequency spectra and scalp topography. Isolating and tracking NBOs over time using algorithms is useful in domains such as brain-computer interfaces or when measuring the EEG effects of experimental manipulations. Previously, we successfully applied modified tensor methods for identifying and tracking NBO activity over time or conditions. We introduced frequency and spatial constraints that greatly improved their physiological plausibility. In this paper we rigorously demonstrate the power and precision of tensor methods to separate, isolate and track NBOs using sources simulated with an anatomical forward model. This allows us to control the attributes of NBOs and validate tensor solutions. We find that tensor methods can accurately identify, separate and track NBOs over time, using realistic sources either alone or in combination, and compare favorably to well-known spatio-spectral decomposition methods for NBO estimation.

Non-contrast computerized tomography (NCCT) and dynamic renal scintigraphy (DRS) in the patients with refractory renal colic.

OBJECTIVES: To assess the importance of combined use of non-contrast computerized tomography (NCCT) and dynamic renal scintigraphy (DRS) in evaluation of patients with refractory flank pain in the emergency department. METHODS: The study involved 64 consecutive patients with refractory renal colic. All patients were evaluated with plain abdominal films kidneys, ureters and bladder (KUB), NCCT and DRS. We assessed the accuracy of different diagnostic procedures and their combinations; in addition, we determined their importance for different steps of evaluation. RESULTS: Urololithiasis was diagnosed in 76.6% (n=49) of the patients. Twenty-nine percent of calculi were > 4 mm. Surgical intervention were performed in 20 patients (40.8%). A combination of NCCT plus DRS yielded the greatest sensitivity (96%) in establishing final diagnosis, however clinical, laboratory and KUB data in combination with DRS, yielded greater specificity (93%) and PPV (97%). Sex (male), WBC (mean 10.2 x 10(3) +/- 3.1) and KUB (calculus > 4 mm) were chosen in the three-step multi-variant analysis, while only male sex was found to be the strongest predictor (p<0.056) of necessity to perform NCCT. In making decision for definitive treatment NCCT and DRS provided the most important information about stone size and obstruction (kappa=0.734, p<0.001 and kappa=0.625, p<0.001), while DRS was selected as the most important diagnostic procedure in the emergency department (kappa=0.527, p<0.001). CONCLUSIONS: In the emergency department, DRS combined with the results of clinical investigation may indicate candidates for hospitalization with emergency intervention. Immediate NCCT must be strongly considered in men with WBC> or =10 x 10(3) and calculi > 4 mm on the KUB.